高尔基体功能的结构方面
Structural aspects of Golgi function.
作者信息
Polishchuk R S, Mironov A A
机构信息
Istituto di Ricerche Farmacologiche Mario Negri, Consorzio Mario Negri Sud, Department of Cell Biology and Oncology, Via Nazionale, 66030 Santa Maria Imbaro, Chieti, Italy.
出版信息
Cell Mol Life Sci. 2004 Jan;61(2):146-58. doi: 10.1007/s00018-003-3353-8.
Abstract
Since its discovery, the Golgi complex has attracted the attention of cell biologists because of its 'fashionable' morphology and central position within the secretory system of the cell. Here, we discuss how the three-dimensional architecture of the Golgi complex relates to its multiple functions in protein sorting and processing, and how an analysis of the morphology of the Golgi complex can help to provide an understanding of the mechanisms involved in transport through this unique organelle.
摘要
自被发现以来，高尔基体因其“时尚”的形态以及在细胞分泌系统中的核心位置，吸引了细胞生物学家的关注。在此，我们将探讨高尔基体的三维结构如何与其在蛋白质分选和加工中的多种功能相关联，以及对高尔基体形态的分析如何有助于理解通过这个独特细胞器进行运输所涉及的机制。
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