Silver Robert D, Djalilian Hamid R, Levine Samuel C, Rimell Frank L
Department of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Laryngoscope. 2002 Oct;112(10):1737-41. doi: 10.1097/00005537-200210000-00005.
High-resolution MRI (MRI) of human inner ear structures provides several advantages over other imaging modalities. High-resolution visualization of inner ear ultrastructure in a noninvasive manner may provide important information about inner ear disease that is not obtainable in other ways. The study was performed to demonstrate the capabilities of MRI at high resolution on the human cochlea, vestibular structures, and facial nerve. Comparative analyses of MRI anatomy with that seen on histological dissection were made. The aim of the study was to define the anatomy of human cadaveric cochlea using a 9.4-Tesla magnetic resonance scanner, currently the most powerful magnetic resonance magnet available.
Experimental pilot study of cadaveric human cochleae.
Serial scanning using a 9.4-Tesla magnetic resonance imager on normal preserved and fresh cadaveric inner ears was performed in different planes.
The images revealed detailed anatomy of the modiolus, utricle, saccule, semicircular canals, and facial nerve. Specifically, identifiable structures within the cochlea included the osseous spiral lamina, Reissner's membrane, membranous spiral lamina, spiral ligament, and others.
Data established through the acquisition of images from cadaver cochlea, facial nerve, and vestibular complex provide a foundation for developing steps for testing temporal bones and, eventually, patients with Meniere's disease and other inner ear disease. The present ongoing project will provide information on baseline images of the inner ear using high-resolution MRI.
与其他成像方式相比，人类内耳结构的高分辨率磁共振成像（MRI）具有多个优势。以非侵入性方式对内耳超微结构进行高分辨率可视化，可能会提供通过其他方式无法获得的有关内耳疾病的重要信息。本研究旨在展示MRI在高分辨率下对人类耳蜗、前庭结构及面神经的成像能力。对MRI解剖结构与组织学解剖所见进行了对比分析。本研究的目的是使用目前可用的最强大的磁共振磁体——9.4特斯拉磁共振扫描仪来明确人类尸体耳蜗的解剖结构。
尸体人类耳蜗的实验性初步研究。
使用9.4特斯拉磁共振成像仪对正常保存的新鲜尸体内耳在不同平面进行连续扫描。
图像显示了蜗轴、椭圆囊、球囊、半规管及面神经的详细解剖结构。具体而言，耳蜗内可识别的结构包括骨螺旋板、Reissner膜、膜性螺旋板、螺旋韧带等。
通过获取尸体耳蜗、面神经及前庭复合体的图像所建立的数据，为制定颞骨检测步骤乃至最终为梅尼埃病及其他内耳疾病患者的检测步骤奠定了基础。当前正在进行的项目将提供使用高分辨率MRI获得的内耳基线图像信息。
