Lane John I, Witte Robert J, Henson Odell W, Driscoll Colin L W, Camp John, Robb Richard A
Mayo Clinic, Rochester, MN 55905, USA.
Clin Anat. 2005 Sep;18(6):409-15. doi: 10.1002/ca.20152.
Anatomic definition of the membranous labyrinth in the clinical setting remains limited despite significant technological advances in magnetic resonance imaging (MRI). Recent developments in ultra-high resolution imaging for use in the research laboratory on small animals and pathologic specimens have given rise to the field of imaging microscopy. We have delineated for the first time the labyrinthine structures in a human temporal bone cadaver specimen using these novel techniques. This approach to the study of the middle and inner ear avoids tissue destruction inherent in histological preparations using standard light microscopy techniques. Part I of this series focused on bony middle and inner ear anatomy with MicrCT. In Part II, we present high-resolution MicroMR images to highlight the utility of this technique in teaching radiologists and otolaryngologists clinically relevant anatomy focusing on the membranous labyrinth. This anatomy can be further enhanced using 3D volume-rendered images. It is hoped that familiarity with these ex vivo anatomic techniques will encourage further developments in the field of high-resolution clinical imaging for patients with temporal bone pathologies.
尽管磁共振成像（MRI）技术取得了重大进展，但临床环境中膜迷路的解剖学定义仍然有限。用于小动物和病理标本研究实验室的超高分辨率成像的最新进展催生了成像显微镜领域。我们首次使用这些新技术在人类颞骨尸体标本中描绘了迷路结构。这种研究中耳和内耳的方法避免了使用标准光学显微镜技术进行组织学制备时固有的组织破坏。本系列的第一部分重点介绍了使用显微CT的骨性中耳和内耳解剖结构。在第二部分中，我们展示了高分辨率显微磁共振图像，以突出该技术在向放射科医生和耳鼻喉科医生传授侧重于膜迷路的临床相关解剖结构方面的效用。使用3D体积渲染图像可以进一步增强这种解剖结构。希望熟悉这些离体解剖技术将鼓励颞骨病理学患者高分辨率临床成像领域的进一步发展。
