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植物蜕皮甾类对哺乳动物的影响、分离与分析。

Phytoecdysteroids effects on mammalians, isolation and analysis.

作者信息

Báthori Mária

机构信息

Department of Pharmacognosy, University of Szeged, Eötvös utca 6, H-6720 Szeged, Hungary.

出版信息

Mini Rev Med Chem. 2002 Jun;2(3):285-93. doi: 10.2174/1389557023406269.

Abstract

Ecdysteroids are known insect moulting hormones, regulating the insects' metamorphosis. At the same time, ecdysteroids reveal beneficial effects on humans and animals alike. Medicinal plants have been subjected to an intensive research, addressing the presence of ecdysteroids. The possible utilization of medicinal plant deals with their use as raw materials for health preparations and also for the isolation of new phytoecdysteroids. Research on the plant ecdysteroids involves two basic lines. Isolation of major compounds and scout their physiological effects; and isolation of minor ecdysteroids to find new compounds. This review summarizes the recent efforts in the ecdysteroid research including their indication as health improvement preparations, chromatography of ecdysteroids and certain methods for identification of new ecdysteroids.

摘要

蜕皮甾类是已知的昆虫蜕皮激素,可调节昆虫的变态发育。同时,蜕皮甾类对人类和动物均显示出有益作用。药用植物已受到深入研究,以确定其中蜕皮甾类的存在。药用植物的潜在用途涉及其作为保健品原料的应用,以及用于分离新的植物蜕皮甾类。对植物蜕皮甾类的研究包括两条基本路线。分离主要化合物并探究其生理效应;分离次要蜕皮甾类以寻找新化合物。本综述总结了蜕皮甾类研究的最新成果,包括其作为健康改善制剂的应用、蜕皮甾类的色谱分析以及鉴定新蜕皮甾类的某些方法。

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