Wessells Hunter
Department of Urology, University of Washington School of Medicine, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104, USA.
Urol Clin North Am. 2002 May;29(2):381-7, vii. doi: 10.1016/s0094-0143(02)00029-0.
Techniques of anterior urethroplasty have evolved over the last 40 years due to advances in tissue transfer techniques and the changing etiology of urethral stricture. The use of free grafts has come full circle from full thickness skin grafts to the current popularity of buccal mucosa grafts. Grafts fell out of favor due to poor results with full thickness skin grafts and the more widespread use of pedicle flaps. Although controversy still exists as to the appropriate use of flaps versus grafts, the evidence does not demonstrate an advantage in outcomes: overall success rates for grafts and flaps are similar (84.3 and 85.9% respectively). Nevertheless, grafting techniques are now considered first line therapy for the majority of strictures that cannot be excised and reanastomosed.
由于组织移植技术的进步以及尿道狭窄病因的变化,前尿道成形术技术在过去40年中不断发展。游离移植物的使用经历了一个轮回,从全厚皮片到如今流行的颊黏膜移植物。由于全厚皮片效果不佳以及带蒂皮瓣的更广泛应用,移植物曾一度失宠。尽管对于皮瓣与移植物的恰当使用仍存在争议,但证据并未表明在治疗效果上有优势:移植物和皮瓣的总体成功率相似(分别为84.3%和85.9%)。然而,对于大多数无法切除并重新吻合的狭窄,移植技术现在被视为一线治疗方法。