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[基层医疗中勃起功能障碍作为健康状况可能标志物的相关因素及对西地那非的反应]

[Erectile dysfunction in primary care as possible marker of health status: associated factors and response to sildenafil].

作者信息

Guirao Sánchez L, García-Giralda Ruiz L, Sandoval Martínez C, Mocciaro Loveccio A

机构信息

Centro de Salud de Alguazas. Gerencia de Atención Primaria de Murcia. Spain.

出版信息

Aten Primaria. 2002 Sep 30;30(5):290-6. doi: 10.1016/s0212-6567(02)79030-6.

Abstract

OBJECTIVES

To find the factors linked to erectile dysfunction, to evaluate this as a possible marker of health status, to analyse the evolution of clinical parameters of associated illnesses and the response to Viagra.Design. Intervention study without a control.

SETTING

Alguazas Health Centre (Murcia).

PARTICIPANTS

All the patients in the programme (125), with a figure on the sexual health in men index (SHIM) below 21.Interventions. Health education and administration of Viagra.

MAIN MEASUREMENTS

Concomitant illnesses, pathologies previously unknown to the patient, changes in erectile function valued on the international index of erectile function (IIEF), and changes in blood pressure, glucaemia and lipids.

RESULTS

Factors linked to erectile dysfunction were diabetes (50.4%), hypertension (33.6%), hypercholesterolaemia (22.4%), urological pathology (12.8%) and mental health disorders (33.6%). The hidden pathology detected was 15 cases of hypertension, 3 diabetes, 2 cardiopathies, 20 dyslipaemias, 3 depressions, 13 anxiety and 5 urological problems. The variations in clinical parameters at 3 months were: glucaemia, -38.3 mg (P<.001, Student s t=-5.186); HbA1c, -0.9 (P<.05, Student s t=-2.16); systolic blood pressure, -16 mm Hg (P<.01, Student s t=-3.486) and diastolic pressure -13 mm Hg (P<.001, Student s t=-4.594); and total cholesterol, -14.2% (P<.001, Student s t=7.01). Erectile function improved by 74% with Viagra.

CONCLUSIONS

2 out of every 3 patients with erectile dysfunction presented associated diseases; one in every 3 were ignorant of their health problem. Monitoring of chronic illnesses improved significantly. Finally, 3 in every 4 responded to Viagra.

摘要

目的

找出与勃起功能障碍相关的因素,评估其作为健康状况潜在标志物的可能性,分析相关疾病临床参数的变化以及对伟哥的反应。设计。无对照的干预研究。

地点

阿尔瓜萨斯健康中心(穆尔西亚)。

参与者

该项目中的所有患者(125名),男性性健康指数(SHIM)低于21。干预措施。健康教育及伟哥给药。

主要测量指标

伴发疾病、患者先前未知的病理情况、根据国际勃起功能指数(IIEF)评估的勃起功能变化,以及血压、血糖和血脂的变化。

结果

与勃起功能障碍相关的因素有糖尿病(50.4%)、高血压(33.6%)、高胆固醇血症(22.4%)、泌尿系统疾病(12.8%)和精神健康障碍(33.6%)。检测出的隐匿病理情况有15例高血压、3例糖尿病、2例心脏病、20例血脂异常、3例抑郁症、13例焦虑症和5例泌尿系统问题。3个月时临床参数的变化为:血糖,-38.3毫克(P<0.001,学生t检验=-5.186);糖化血红蛋白,-0.9(P<0.05,学生t检验=-2.16);收缩压,-16毫米汞柱(P<0.01,学生t检验=-3.486),舒张压-13毫米汞柱(P<0.001,学生t检验=-4.594);总胆固醇,-14.2%(P<0.001,学生t检验=7.01)。使用伟哥后勃起功能改善了74%。

结论

每3名勃起功能障碍患者中有2名患有相关疾病;每3名中有1名对自身健康问题不知情。慢性病监测有显著改善。最后,每4名患者中有3名对伟哥有反应。

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