基因yjfQ编码yjfR-X操纵子（ula）的阻遏物，该操纵子参与大肠杆菌中的L-抗坏血酸代谢。
The gene yjfQ encodes the repressor of the yjfR-X regulon (ula), which is involved in L-ascorbate metabolism in Escherichia coli.
作者信息
Campos Evangelina, Aguilar Juan, Baldoma Laura, Badia Josefa
机构信息
Department of Biochemistry, Faculty of Pharmacy, University of Barcelona, 08028 Barcelona, Spain.
出版信息
J Bacteriol. 2002 Nov;184(21):6065-8. doi: 10.1128/JB.184.21.6065-6068.2002.
Abstract
Mutations in yjfQ allowed us to identify this gene as the regulator of the operon yjfS-X (ula operon), reported to be involved in L-ascorbate metabolism. Inactivation of this gene renders constitutive the expression of the ula operon, indicating that YjfQ acts as a repressor. We also demonstrate that this repressor regulates the nearby yjfR gene, which in this way constitutes a regulon with the ula operon.
摘要
yjfQ基因的突变使我们能够将该基因鉴定为yjfS-X操纵子（ula操纵子）的调节因子，据报道该操纵子参与L-抗坏血酸代谢。该基因的失活导致ula操纵子的表达组成型，表明YjfQ作为阻遏物发挥作用。我们还证明，这种阻遏物调节附近的yjfR基因，从而与ula操纵子构成一个调控子。
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