The discovery of susceptibility genes for mental disorders.
作者信息
Cloninger C Robert
机构信息
Departments of Psychiatry and Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA.
出版信息
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13365-7. doi: 10.1073/pnas.222532599. Epub 2002 Oct 8.
Abstract
摘要
相似文献
1
The discovery of susceptibility genes for mental disorders.
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13365-7. doi: 10.1073/pnas.222532599. Epub 2002 Oct 8.
2
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia.将新的人类基因G72和D-氨基酸氧化酶基因与精神分裂症联系起来的遗传和生理数据。
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13675-80. doi: 10.1073/pnas.182412499. Epub 2002 Oct 3.
3
N-methyl-D-aspartate receptor hypofunction in schizophrenia could arise from reduced cortical connectivity rather than receptor dysfunction.
Arch Gen Psychiatry. 1997 Jun;54(6):578-80. doi: 10.1001/archpsyc.1997.01830180096017.
4
Schizophrenia susceptibility and NMDA-receptor mediated signalling: an association study involving 32 tagSNPs of DAO, DAOA, PPP3CC, and DTNBP1 genes.精神分裂症易感性与 NMDA 受体介导的信号转导：一项包含 DAO、DAOA、PPP3CC 和 DTNBP1 基因 32 个标签 SNP 的关联研究。
BMC Med Genet. 2013 Mar 9;14:33. doi: 10.1186/1471-2350-14-33.
5
The N-methyl-D-aspartate receptor and schizophrenia.
Isr J Med Sci. 1996 May;32(5):275-81.
6
[Mutant mouse lacking D-amino-acid oxidase activity].
Seikagaku. 2008 Apr;80(4):337-43.
7
Preliminary evidence for a link between schizophrenia and NMDA-glycine site receptor ligand metabolic enzymes, d-amino acid oxidase (DAAO) and kynurenine aminotransferase-1 (KAT-1).
Brain Res. 2006 Aug 23;1106(1):205-210. doi: 10.1016/j.brainres.2006.05.082. Epub 2006 Jul 7.
8
Association analyses of the DAOA/G30 and D-amino-acid oxidase genes in schizophrenia: further evidence for a role in schizophrenia.精神分裂症中DAOA/G30基因与D-氨基酸氧化酶基因的关联分析：对其在精神分裂症中作用的进一步证据
Neuromolecular Med. 2007;9(2):169-77. doi: 10.1007/BF02685890.
9
Disconnection and cognitive dysmetria in schizophrenia.精神分裂症中的连接中断与认知性辨距不良
Am J Psychiatry. 2005 Mar;162(3):429-32. doi: 10.1176/appi.ajp.162.3.429.
10
Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice.遗传缺失 D-氨基酸氧化酶活性可逆转小鼠的精神分裂样表型。
Genes Brain Behav. 2010 Feb;9(1):11-25. doi: 10.1111/j.1601-183X.2009.00529.x. Epub 2009 Aug 5.
引用本文的文献
1
The revised Temperament and Character Inventory: normative data by sex and age from a Spanish normal randomized sample.修订版气质与性格量表：来自西班牙正常随机样本的按性别和年龄划分的常模数据。
PeerJ. 2015 Dec 22;3:e1481. doi: 10.7717/peerj.1481. eCollection 2015.
2
The relationship between self-report of depression and media usage.抑郁症的自我报告与媒体使用之间的关系。
Front Hum Neurosci. 2014 Sep 12;8:712. doi: 10.3389/fnhum.2014.00712. eCollection 2014.
3
The interaction of polymorphisms of IL10 and DBH was associated with general symptoms of PANSS with TD in Chinese Han schizophrenic patients.IL10 和 DBH 多态性的相互作用与中国汉族精神分裂症患者 TD 时 PANSS 的一般症状相关。
PLoS One. 2013 Aug 7;8(8):e70963. doi: 10.1371/journal.pone.0070963. eCollection 2013.
4
Does the bipolar disorder-associated CACNA1C gene confer susceptibility to schizophrenia in Han Chinese?双相情感障碍相关的 CACNA1C 基因是否会使汉族人群易患精神分裂症？
J Mol Neurosci. 2013 Oct;51(2):474-7. doi: 10.1007/s12031-013-0079-4. Epub 2013 Jul 31.
5
The application of selective reaction monitoring confirms dysregulation of glycolysis in a preclinical model of schizophrenia.选择性反应监测的应用证实了精神分裂症临床前模型中糖酵解的失调。
BMC Res Notes. 2012 Mar 15;5:146. doi: 10.1186/1756-0500-5-146.
6
Modeling brain dynamics using computational neurogenetic approach.运用计算神经遗传学方法对大脑动力学进行建模。
Cogn Neurodyn. 2008 Dec;2(4):319-34. doi: 10.1007/s11571-008-9061-1. Epub 2008 Sep 16.
7
Genetics of bipolar disorder.双相情感障碍的遗传学
Dialogues Clin Neurosci. 2008;10(2):141-52. doi: 10.31887/DCNS.2008.10.2/maescamilla.
8
Kraepelin, biological psychiatry, and beyond.克雷佩林、生物精神病学及其他领域。
Eur Arch Psychiatry Clin Neurosci. 2008 Jun;258 Suppl 2:29-32. doi: 10.1007/s00406-008-2006-1.
9
Comprehensive analysis of polymorphisms throughout GAD1 gene: a family-based association study in schizophrenia.对整个GAD1基因多态性的综合分析：一项精神分裂症的基于家系的关联研究。
J Neural Transm (Vienna). 2008;115(3):513-9. doi: 10.1007/s00702-007-0844-z. Epub 2008 Mar 12.
10
Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample.对409个有精神分裂症的欧洲裔和非裔美国家庭进行全基因组连锁扫描：在合并样本中，8p23.3 - p21.2和11p13.1 - q14.1处存在连锁的提示性证据。
Am J Hum Genet. 2006 Feb;78(2):315-33. doi: 10.1086/500272. Epub 2006 Jan 3.
本文引用的文献
1
Personality disorders and physical comorbidities: a complex relationship.人格障碍与躯体共病：复杂的关系。
Curr Opin Psychiatry. 2019 Sep;32(5):435-441. doi: 10.1097/YCO.0000000000000536.
2
Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia.将新的人类基因G72和D-氨基酸氧化酶基因与精神分裂症联系起来的遗传和生理数据。
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13675-80. doi: 10.1073/pnas.182412499. Epub 2002 Oct 3.
3
Neuregulin 1 and susceptibility to schizophrenia.神经调节蛋白1与精神分裂症易感性
Am J Hum Genet. 2002 Oct;71(4):877-92. doi: 10.1086/342734. Epub 2002 Jul 23.
4
Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia.位于6p22.3区域的基因DTNBP1（小鼠dysbindin基因在人类中的直系同源基因）的遗传变异与精神分裂症相关。
Am J Hum Genet. 2002 Aug;71(2):337-48. doi: 10.1086/341750. Epub 2002 Jul 3.
5
Genetic linkage to schizophrenia at chromosome 15q14.
Am J Med Genet. 2001 Dec 8;105(8):655-7. doi: 10.1002/ajmg.1548.
6
A perspective on epistasis: limits of models displaying no main effect.上位性的观点：无主效应模型的局限性。
Am J Hum Genet. 2002 Feb;70(2):461-71. doi: 10.1086/338759. Epub 2002 Jan 8.
7
Storage, recall, and novelty detection of sequences by the hippocampus: elaborating on the SOCRATIC model to account for normal and aberrant effects of dopamine.海马体对序列的存储、回忆及新颖性检测：详述苏格拉底模型以解释多巴胺的正常及异常作用。
Hippocampus. 2001;11(5):551-68. doi: 10.1002/hipo.1071.
8
NMDA receptor regulation of memory and behavior in humans.NMDA受体对人类记忆和行为的调节。
Hippocampus. 2001;11(5):529-42. doi: 10.1002/hipo.1069.
9
Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: schizophrenia linkage collaborative group III.5号染色体长臂、6号染色体长臂、10号染色体短臂和13号染色体短臂上精神分裂症候选区域的多中心连锁研究：精神分裂症连锁协作组III
Am J Hum Genet. 2000 Sep;67(3):652-63. doi: 10.1086/303041. Epub 2000 Aug 2.
10
Pharmacogenetics and the practice of medicine.药物遗传学与医学实践
Nature. 2000 Jun 15;405(6788):857-65. doi: 10.1038/35015728.
Zotero 插件