Riechman Steven E, Schoen Robert E, Weissfeld Joel L, Thaete F Leland, Kriska Andrea M
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Obes Res. 2002 Oct;10(10):1065-73. doi: 10.1038/oby.2002.144.
Physical inactivity, abdominal fat, and age are known risk factors for diabetes, cardiovascular disease, and certain cancers. Previous evidence supports an inverse relationship between physical activity (PA) and abdominal fat estimated by waist circumference. However, few investigations used computed tomography (CAT) scanning for precise measures of abdominal fat.
Sixty-five female and 106 male (age, 64.5 +/- 5.2 years) participants in the Prostate, Lung, Colon and Ovarian Cancer Screening Trial underwent a cross-sectional L4-L5 CAT scan to differentiate visceral adipose tissue (VAT). Subjects were also interviewed by phone to determine PA and physical difficulties (PD).
Women had lower VAT (170 +/- 84 vs. 205 +/- 95 cm(2), p = 0.014), lower VAT/total fat (29.9 +/- 7.2% vs. 42.6 +/- 10.2%, p < 0.001), and higher total fat (596 +/- 385 vs. 482 +/- 183 cm(2), p = 0.010) than men. PA was inversely correlated to VAT (r = -0.164, p = 0.034) and total fat (r = -0.231, p = 0.003) in men and women. Those who reported a PD had higher VAT (249 vs. 180 cm(2), p < 0.001) and total fat (652 vs. 500 cm(2), p = 0.008). Multiple regression analysis indicated total PA and PD were independently associated to VAT and total fat.
This investigation suggests a beneficial effect of PA and a negative influence of PD on abdominal fat accumulation. Although the cross-sectional design limits cause-effect designations, these results are consistent with other studies showing PA/abdominal fat relation.
缺乏体育活动、腹部脂肪堆积和年龄是已知的糖尿病、心血管疾病及某些癌症的风险因素。先前的证据支持体育活动（PA）与通过腰围估算的腹部脂肪之间存在负相关关系。然而，很少有研究使用计算机断层扫描（CAT）来精确测量腹部脂肪。
前列腺、肺、结肠和卵巢癌筛查试验中的65名女性和106名男性参与者（年龄64.5±5.2岁）接受了L4 - L5水平的横断面CAT扫描，以区分内脏脂肪组织（VAT）。还通过电话采访受试者以确定其体育活动情况和身体困难（PD）。
女性的内脏脂肪组织含量较低（170±84 vs. 205±95 cm²，p = 0.014），内脏脂肪组织与总脂肪的比例较低（29.9±7.2% vs. 42.6±10.2%，p < 0.001），总脂肪含量较高（596±385 vs. 482±183 cm²，p = 0.010），均高于男性。男性和女性的体育活动与内脏脂肪组织（r = -0.164，p = 0.034）及总脂肪（r = -0.231，p = 0.003）均呈负相关。报告有身体困难的人内脏脂肪组织含量较高（249 vs. 180 cm²，p < 0.001），总脂肪含量也较高（652 vs. 500 cm²，p = 0.008）。多元回归分析表明，总的体育活动和身体困难与内脏脂肪组织及总脂肪独立相关。
本研究表明体育活动具有有益作用，而身体困难对腹部脂肪堆积有负面影响。尽管横断面设计限制了因果关系的判定，但这些结果与其他显示体育活动与腹部脂肪关系的研究一致。
