Yang Woojung, Lee Jae-Woo, Kim Yonghwan, Lee Jong Hun, Kang Hee-Taik
Department of Family Medicine, Chungbuk National University Hospital, Cheongju 28644, Korea.
Department of Food Science and Biotechnology, Gachon University, Seongnam 13120, Korea.
J Clin Med. 2020 Nov 27;9(12):3856. doi: 10.3390/jcm9123856.
(1) Background: Omega-3 fatty acids (ω3FAs) are known to improve protein anabolism, increase the sensitivity to anabolic stimuli, decrease lipogenesis, and stimulate lipid oxidation. We aim to investigate whether ω3FAs are associated with the prevalence of sarcopenic obesity (SO). (2) Methods: Data were obtained from the 2014-2018 Korean National Health and Nutrition Examination Survey. The ratio of daily ω3FA intake to energy intake (ω3FA ratio) was categorized into four quartile groups. (3) Results: The prevalence of SO from Q1 to Q4 was 8.9%, 11.3%, 11.0%, and 9.8% respectively, in men and 17.4%, 14.0%, 13.9%, and 10.1% respectively, in women. The ω3FA ratio in individuals with and without SO were 1.0% and 0.9% in men (-value = 0.271) respectively, and 0.8% and 1.0% in women (-value = 0.017), respectively. Compared with Q1, odds ratios (95% confidence intervals) of Q2, Q3, and Q4 of ω3FA ratios were 1.563 (0.802-3.047), 1.246 (0.611-2.542), and 0.924 (0.458-1.864) respectively, in men and 0.663 (0.379-1.160), 0.640 (0.372-1.102), and 0.246 (0.113-0.534) respectively, in women, after fully adjusting for confounding factors. (4) Conclusions: The ω3FA ratio was significantly higher in older females without SO than in older females with SO. The ω3FA ratio was associated with the prevalence of SO in elderly females.
(1) 背景：已知ω-3脂肪酸（ω3FAs）可改善蛋白质合成代谢、提高对合成代谢刺激的敏感性、减少脂肪生成并刺激脂质氧化。我们旨在研究ω3FAs是否与肌肉减少性肥胖（SO）的患病率相关。(2) 方法：数据来自2014 - 2018年韩国国家健康与营养检查调查。每日ω3FA摄入量与能量摄入量的比值（ω3FA比值）被分为四个四分位数组。(3) 结果：男性中，从第一四分位数组（Q1）到第四四分位数组（Q4）的SO患病率分别为8.9%、11.3%、11.0%和9.8%；女性中分别为17.4%、14.0%、13.9%和10.1%。有和没有SO的个体中，男性的ω3FA比值分别为1.0%和0.9%（P值 = 0.271），女性分别为0.8%和1.0%（P值 = 0.017）。在对混杂因素进行充分调整后，男性中ω3FA比值的第二、第三和第四四分位数组与第一四分位数组相比，比值比（95%置信区间）分别为1.563（0.802 - 3.047）、1.246（0.611 - 2.542）和0.924（0.458 - 1.864）；女性中分别为0.663（0.379 - 1.160）、0.640（0.372 - 1.102）和0.246（0.113 - 0.534）。(4) 结论：没有SO的老年女性的ω3FA比值显著高于患有SO的老年女性。ω3FA比值与老年女性SO的患病率相关。
