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癫痫的电刺激:海马病灶的刺激。

Electrical stimulation for epilepsy: stimulation of hippocampal foci.

作者信息

Velasco F, Velasco M, Velasco A L, Menez D, Rocha L

机构信息

Unit for Stereotactic and Functional Neurosurgery, General Hospital, Mexico City, Mexico.

出版信息

Stereotact Funct Neurosurg. 2001;77(1-4):223-7. doi: 10.1159/000064610.

DOI:10.1159/000064610
PMID:12378080
Abstract

Subacute and chronic continuous electrical stimulation at the epileptic focus in the hippocampus or parahippocampal cortex at 130 Hz, 0.21-1.0 ms, 2.5-3.5 V (about 200-300 microA) induces a decrease in focal EEG epileptic interictal activity and also in the occurrence of clinical seizures. This may represent an alternative for the treatment of temporal lobe seizures originated in bilateral independent temporal lobe foci or occurring in patients where one is uncertain whether memory deficit might result from ablative procedures.

摘要

在海马体或海马旁回皮质的癫痫病灶处以130赫兹、0.21 - 1.0毫秒、2.5 - 3.5伏(约200 - 300微安)进行亚急性和慢性连续电刺激,可使局部脑电图癫痫发作间期活动减少,临床癫痫发作次数也减少。这可能是治疗起源于双侧独立颞叶病灶的颞叶癫痫或不确定记忆缺陷是否可能由切除手术导致的患者癫痫发作的一种替代方法。

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Electrical stimulation for epilepsy: stimulation of hippocampal foci.癫痫的电刺激:海马病灶的刺激。
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