Faraj Zoulikha, Khattabi Asmae, Soulaymani Rachida
Centre anti-poison du Maroc, INH, BP:769, 11400 Rabat-Agdal Maroc.
Presse Med. 2002 Sep 21;31(30):1410-3.
Although the existence of classical occupational asthma is well known and described after fairly prolonged exposure to moderate levels of air-contaminators, authentic asthma can be provoked by rapid single inhalation of a high dosed corrosive gas: this is Brooks' syndrome.
A 30 year-old woman, without respiratory past history and no atopy presented with post-toxic asthma following a single accidental inhalation of hydrochloric acid. The diagnosis was established on the 8 criteria of Brooks and the clinical outcome remained stable with, however, excellent response to the inhalation of broncho-dilatators during asthma attacks.
The relationship with the accidental inhalation may have been ignored by the victim. The outcome of this syndrome is good in 50% of cases; in 25% the symptomatology worsens and in the remaining 25% it remains stable.
虽然经典职业性哮喘的存在已为人熟知,且在长时间接触中等浓度空气污染物后会有相关描述,但单次快速吸入高剂量腐蚀性气体也可引发真性哮喘:这就是布鲁克斯综合征。
一名30岁女性,无呼吸疾病既往史且无特应性,在单次意外吸入盐酸后出现中毒后哮喘。根据布鲁克斯的8条标准确诊,临床症状保持稳定,不过在哮喘发作时吸入支气管扩张剂反应良好。
受害者可能忽略了与意外吸入的关系。该综合征50%的病例预后良好;25%症状加重,其余25%保持稳定。