Giovino Gary A
Department of Cancer Prevention, Epidemiology, and Biostatistics, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, New York, NY 14263, USA.
Oncogene. 2002 Oct 21;21(48):7326-40. doi: 10.1038/sj.onc.1205808.
Efforts to understand trends in and patterns of lung cancer are well served by studies of trends in and patterns of tobacco use. In the United States, the manufactured cigarette emerged as the tobacco product of choice shortly after the turn of the twentieth century. Lung cancer emerged after years of inhalation of cigarette smoke, first among men and then among women. The massive public health education campaign that began after scientists recognized the dangers of cigarette smoking has contributed to large reductions in cigarette use and subsequent smoking-attributable morbidity and mortality. Since 1965, the prevalence of cigarette smoking among US adults has declined by almost half, with positive trends observed among persons in almost all sociodemographic groups and efforts to reduce disparities recognized as an important goal in public health. An epidemiologic approach to understanding and controlling patterns of tobacco use is proposed. The model focuses on the agent (tobacco products), host (consumer or potential consumer), vector (tobacco companies and other users), and environment (with influences from families, social sources, culture, history, politics, law, and media). Accelerating progress in reducing tobacco use will accelerate reductions in tobacco-attributable morbidity and mortality.
通过对烟草使用趋势和模式的研究,有助于了解肺癌的趋势和模式。在美国,二十世纪初过后不久,机制卷烟成为了首选的烟草产品。经过多年吸入香烟烟雾后,肺癌首先在男性中出现,随后在女性中出现。在科学家认识到吸烟的危害后开展的大规模公共健康教育运动,促使卷烟使用量大幅减少,以及随后与吸烟相关的发病率和死亡率的下降。自1965年以来,美国成年人吸烟率下降了近一半,几乎所有社会人口群体的吸烟率都呈现出积极的下降趋势,减少差异的努力被视为公共卫生的一个重要目标。本文提出了一种理解和控制烟草使用模式的流行病学方法。该模型侧重于致病因子(烟草产品)、宿主(消费者或潜在消费者)、媒介(烟草公司和其他使用者)和环境(受到家庭、社会来源、文化、历史、政治、法律和媒体的影响)。加快减少烟草使用的进展将加速降低与烟草相关的发病率和死亡率。