Subach Ruth Ann, Marx Michael A
Western University of Health Sciences, College of Pharmacy, Pomona, CA 91766, USA.
Ren Fail. 2002 Sep;24(5):609-14. doi: 10.1081/jdi-120013964.
Pruritus is a common complaint among end stage renal disease patients and has been associated with poor outcome. We characterized this problem at our outpatient hemodialysis unit. Seventy patients were surveyed over a two-day period. A visual analog scale was used to evaluate the intensity of itching. Location of itching and temporal relationship to dialysis was assessed by questionnaire. Laboratory parameters were evaluated to differentiate between those who itched and those who did not itch. Seventy percent of patients reported pruritus either during and/or between hemodialysis sessions. Itch intensity ranged from mild to severe. Forty-five percent of patients itched in three or more areas with the back and legs most commonly reported. Laboratory parameters were unable to differentiate between patients who itched and those who did not itch. Itching remains a common problem in hemodialysis patients. New treatments for patients resistant to standard therapies are needed.
瘙痒是终末期肾病患者的常见主诉，且与不良预后相关。我们在门诊血液透析单元对这一问题进行了特征描述。在两天时间内对70名患者进行了调查。使用视觉模拟量表评估瘙痒强度。通过问卷调查评估瘙痒部位以及与透析的时间关系。评估实验室参数以区分瘙痒患者和无瘙痒患者。70%的患者在血液透析期间和/或透析间期报告有瘙痒。瘙痒强度从轻度到重度不等。45%的患者在三个或更多部位出现瘙痒，最常报告的部位是背部和腿部。实验室参数无法区分瘙痒患者和无瘙痒患者。瘙痒在血液透析患者中仍然是一个常见问题。需要为对标准疗法耐药的患者开发新的治疗方法。
