• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Enzyme-catalyzed antimicrobial activation.

作者信息

Hamilton-Miller J M T

出版信息

Antimicrob Agents Chemother. 2002 Nov;46(11):3692; author reply 3692. doi: 10.1128/AAC.46.11.3692.2002.

DOI:10.1128/AAC.46.11.3692.2002
PMID:12384397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC128745/
Abstract
摘要

相似文献

1
Enzyme-catalyzed antimicrobial activation.酶催化抗菌激活。
Antimicrob Agents Chemother. 2002 Nov;46(11):3692; author reply 3692. doi: 10.1128/AAC.46.11.3692.2002.
2
beta-Lactamase hydrolysis of cephalosporin 3'-quinolone esters, carbamates, and tertiary amines.头孢菌素3'-喹诺酮酯、氨基甲酸酯和叔胺的β-内酰胺酶水解作用
Antimicrob Agents Chemother. 1994 May;38(5):959-62. doi: 10.1128/AAC.38.5.959.
3
Clinical challenges in addressing resistance to antimicrobial drugs in the twenty-first century.21世纪应对抗菌药物耐药性的临床挑战。
Clin Pharmacol Ther. 2009 Sep;86(3):336-9. doi: 10.1038/clpt.2009.122. Epub 2009 Jul 1.
4
Biotransformation of monoterpenoids and their antimicrobial activities.单萜类化合物的生物转化及其抗菌活性。
Phytomedicine. 2014 Oct 15;21(12):1597-626. doi: 10.1016/j.phymed.2014.05.011. Epub 2014 Aug 27.
5
Molecular properties prediction, docking studies, and antimicrobial screening of 1,3,4-thiadiazole and s-triazole derivatives.1,3,4-噻二唑和均三唑衍生物的分子性质预测、对接研究及抗菌筛选
Curr Comput Aided Drug Des. 2014 Mar;10(1):3-14. doi: 10.2174/15734099113096660033.
6
Metallo-β-lactamase-catalyzed hydrolysis of cephalosporins: some mechanistic insights into the effect of heterocyclic thiones on enzyme activity.金属β-内酰胺酶催化头孢菌素的水解：杂环硫酮对酶活性影响的一些机理见解。
Inorg Chem. 2011 Feb 7;50(3):749-56. doi: 10.1021/ic100253k. Epub 2011 Jan 6.
7
Studies of antimicrobial resistance genes using DNA probes.使用DNA探针研究抗微生物耐药基因。
Antimicrob Agents Chemother. 1986 May;29(5):721-5. doi: 10.1128/AAC.29.5.721.
8
Fungal biotransformation of tanshinone results in [4+2] cycloaddition with sorbicillinol: evidence for enzyme catalysis and increased antibacterial activity.丹参酮的真菌生物转化导致[4+2]环加成与蛇床素醇反应：酶催化和增强抗菌活性的证据。
Appl Microbiol Biotechnol. 2016 Oct;100(19):8349-57. doi: 10.1007/s00253-016-7488-6. Epub 2016 May 20.
9
Mechanism of action of NB2001 and NB2030, novel antibacterial agents activated by beta-lactamases.新型β-内酰胺酶激活抗菌剂NB2001和NB2030的作用机制
Antimicrob Agents Chemother. 2004 Feb;48(2):477-83. doi: 10.1128/AAC.48.2.477-483.2004.
10
Synergistic interactions of phytochemicals with antimicrobial agents: Potential strategy to counteract drug resistance.植物化学物质与抗菌剂的协同作用：克服耐药性的潜在策略。
Chem Biol Interact. 2019 Aug 1;308:294-303. doi: 10.1016/j.cbi.2019.05.050. Epub 2019 May 31.

本文引用的文献

1
NB2001, a novel antibacterial agent with broad-spectrum activity and enhanced potency against beta-lactamase-producing strains.NB2001是一种新型抗菌剂，具有广谱活性，对产β-内酰胺酶菌株的效力增强。
Antimicrob Agents Chemother. 2002 May;46(5):1262-8. doi: 10.1128/AAC.46.5.1262-1268.2002.
2
A novel approach to thymidylate synthase as a target for cancer chemotherapy.
Mol Pharmacol. 2001 Mar;59(3):446-52. doi: 10.1124/mol.59.3.446.
3
Enzyme-catalyzed therapeutic agent (ECTA) design: activation of the antitumor ECTA compound NB1011 by thymidylate synthase.酶催化治疗剂（ECTA）设计：胸苷酸合成酶激活抗肿瘤ECTA化合物NB1011
Biochem Pharmacol. 2001 Jan 15;61(2):179-89. doi: 10.1016/s0006-2952(00)00542-6.
4
beta-lactams: variations on a chemical theme, with some surprising biological results.β-内酰胺类：化学主题的变体，带来了一些惊人的生物学结果。
J Antimicrob Chemother. 1999 Dec;44(6):729-34. doi: 10.1093/jac/44.6.729.
5
Triclosan: applications and safety.
Am J Infect Control. 1996 Jun;24(3):209-18. doi: 10.1016/s0196-6553(96)90017-6.
6
Dual-action antibiotic hybrids.双效抗生素杂合物
J Antimicrob Chemother. 1994 Feb;33(2):197-200. doi: 10.1093/jac/33.2.197.
7
Cephalosporin derivatives of doxorubicin as prodrugs for activation by monoclonal antibody-beta-lactamase conjugates.作为前药用于通过单克隆抗体 - β - 内酰胺酶缀合物激活的阿霉素头孢菌素衍生物。
J Med Chem. 1995 Apr 14;38(8):1380-5. doi: 10.1021/jm00008a016.
8
A new cephalosporin with a dual mode of action.一种具有双重作用模式的新型头孢菌素。
Antimicrob Agents Chemother. 1976 Aug;10(2):245-8. doi: 10.1128/AAC.10.2.245.