Sánchez-Alemán Miguel A, Uribe-Salas Felipe, Conde-González Carlos J
Centro de Investigaciones sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México.
Salud Publica Mex. 2002 Sep-Oct;44(5):442-7.
To estimate the prevalence of Human papillomavirus (HPV) among university students and to use it as a biological marker to assess sexual behavior.
A cross-sectional study was carried out between 2000 and 2001 among 194 students at Universidad Autónoma del Estado de Morelos, Mexico. A data collection instrument was applied and genital samples were taken to detect oncogenic HPV DNA. Data were analyzed using the chi-squared test and odds ratios.
Overall HPV prevalence was 14.4%. Women who had had two or more sexual partners during the previous year showed a greater risk of HPV infection (OR 6.0, 95% CI 1.7-21.1), as did women who had used oral contraceptives and spermicides at their latest intercourse (OR 3.0, 95% CI 1.0-8.7). Males who consumed cocaine were at a greater risk of HPV infection (OR 7.6, 95% CI 1.3-45.1).
HPV prevalence is relatively high. HPV is a reliable biological marker of sexual behavior among females. A greater sample size may be needed to assess its reliability among men.
评估大学生中人乳头瘤病毒（HPV）的感染率，并将其作为评估性行为的生物学指标。
2000年至2001年间，对墨西哥莫雷洛斯州自治大学的194名学生开展了一项横断面研究。应用了一种数据收集工具，并采集生殖器样本以检测致癌性HPV DNA。采用卡方检验和比值比分析数据。
HPV总体感染率为14.4%。前一年有两个或更多性伴侣的女性感染HPV的风险更高（比值比6.0，95%可信区间1.7 - 21.1），最近一次性交时使用口服避孕药和杀精剂的女性也是如此（比值比3.0，95%可信区间1.0 - 8.7）。吸食可卡因的男性感染HPV的风险更高（比值比7.6，95%可信区间1.3 - 45.1）。
HPV感染率相对较高。HPV是女性性行为的可靠生物学指标。可能需要更大样本量来评估其在男性中的可靠性。
