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脊髓型颈椎病的治疗方法:保守治疗与手术治疗效果的3年随访研究

Approaches to spondylotic cervical myelopathy: conservative versus surgical results in a 3-year follow-up study.

作者信息

Kadanka Zdenek, Mares Miroslav, Bednaník Josef, Smrcka Vladimír, Krbec Martin, Stejskal Lubor, Chaloupka Richard, Surelová Dagmar, Novotný Oldrich, Urbánek Igor, Dusek Ladislav

机构信息

Department of Neurology, Faculty Hospital of Brno, Czech Republic.

出版信息

Spine (Phila Pa 1976). 2002 Oct 15;27(20):2205-10; discussion 2210-1. doi: 10.1097/01.BRS.0000029255.77224.BB.

Abstract

STUDY DESIGN

A 3-year prospective randomized study was conducted.

OBJECTIVE

To compare conservative and operative treatments of mild and moderate, nonprogressive, and slowly progressive forms of spondylotic cervical myelopathy.

SUMMARY OF BACKGROUND

DATA It is not known whether the results of decompressive surgery for the mild and moderate forms of spondylotic cervical myelopathy are any better than those of the conservative approach.

METHODS

For this study, 68 patients were randomized into two groups. Group A, treated conservatively, consisted of 35 subjects, whereas Group B, treated surgically, was composed of 33 patients. The clinical outcome was evaluated by modified JOA score, timed 10-m walk, the score for daily activities recorded by video and evaluated by two observers blinded to the type of therapy, and subjective assessment by the patients themselves at months 6, 12, 24, and 36 of the follow-up period.

RESULTS

There was, on the average, no significant deterioration in mJOA score in the two groups over the 3-year follow-up period, but there was a slightly expressed decrease in the self-evaluation score in Group B, and a slight deterioration of the score for daily activities in Group A. Comparison of the two groups showed a significant difference in the timed 10-m walk test favoring group A, but no difference in mJOA score or self-evaluation by the patients themselves, with the exception of a better score at month 6 in favor of Group B.

CONCLUSIONS

The 3-year follow-up study did not show, on the average, that the surgery is superior to conservative treatment for mild and moderate forms of spondylotic cervical myelopathy.

摘要

研究设计

进行了一项为期3年的前瞻性随机研究。

目的

比较轻度和中度、非进行性及缓慢进行性脊髓型颈椎病的保守治疗和手术治疗效果。

背景资料总结

对于轻度和中度脊髓型颈椎病,减压手术的效果是否优于保守治疗尚不清楚。

方法

本研究中,68例患者被随机分为两组。A组为保守治疗组,共35例;B组为手术治疗组,共33例。通过改良JOA评分、10米定时步行测试、由两名对治疗类型不知情的观察者通过视频记录并评估的日常活动评分以及患者在随访期6个月、12个月、24个月和36个月时的主观评估来评价临床结果。

结果

在3年的随访期内,两组患者的改良JOA评分平均无显著恶化,但B组的自我评估评分略有下降,A组的日常活动评分略有恶化。两组比较显示,在10米定时步行测试中A组有显著差异,但改良JOA评分或患者自我评估无差异,除了在6个月时B组评分较好。

结论

3年的随访研究平均未显示手术治疗对于轻度和中度脊髓型颈椎病优于保守治疗。

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