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退行性颈椎脊髓病:临床表现、评估及自然病史

Degenerative Cervical Myelopathy: Clinical Presentation, Assessment, and Natural History.

作者信息

Lannon Melissa, Kachur Edward

机构信息

Division of Neurosurgery, McMaster University, Hamilton, ON L8S 4L8, Canada.

出版信息

J Clin Med. 2021 Aug 17;10(16):3626. doi: 10.3390/jcm10163626.

Abstract

Degenerative cervical myelopathy (DCM) is a leading cause of spinal cord injury and a major contributor to morbidity resulting from narrowing of the spinal canal due to osteoarthritic changes. This narrowing produces chronic spinal cord compression and neurologic disability with a variety of symptoms ranging from mild numbness in the upper extremities to quadriparesis and incontinence. Clinicians from all specialties should be familiar with the early signs and symptoms of this prevalent condition to prevent gradual neurologic compromise through surgical consultation, where appropriate. The purpose of this review is to familiarize medical practitioners with the pathophysiology, common presentations, diagnosis, and management (conservative and surgical) for DCM to develop informed discussions with patients and recognize those in need of early surgical referral to prevent severe neurologic deterioration.

摘要

退行性颈椎脊髓病(DCM)是脊髓损伤的主要原因,也是骨关节炎改变导致椎管狭窄所致发病的主要因素。这种狭窄会产生慢性脊髓压迫和神经功能障碍,症状多样,从上肢轻度麻木到四肢瘫痪和大小便失禁不等。各专业的临床医生都应熟悉这种常见疾病的早期体征和症状,以便在适当情况下通过手术会诊防止神经功能逐渐受损。本综述的目的是使医学从业者熟悉DCM的病理生理学、常见表现、诊断及管理(保守和手术),以便与患者进行明智的讨论,并识别那些需要早期手术转诊以防止严重神经功能恶化的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/618d/8396963/fae06825e4bc/jcm-10-03626-g001.jpg

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