Greaves David R, Channon Keith M
Sir William Dunn School of Pathology, University of Oxford, South Parks Road, UK OX1 3RE.
Trends Immunol. 2002 Nov;23(11):535-41. doi: 10.1016/s1471-4906(02)02331-1.
Recent studies have highlighted the role of inflammatory mediators and the cells of the innate and adaptive immune response in the initiation, growth and rupture of atherosclerotic plaques. Viewing this form of vascular pathology as a modified form of chronic inflammation suggests new avenues for therapeutic intervention in cardiovascular disease.
近期研究突显了炎症介质以及先天性和适应性免疫反应细胞在动脉粥样硬化斑块的起始、生长和破裂过程中的作用。将这种血管病理学形式视为慢性炎症的一种改良形式，为心血管疾病的治疗干预提供了新途径。
