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Fulminant hepatic failure after the start of an efavirenz-based HAART regimen in a treatment-naive female AIDS patient without hepatitis virus co-infection.

作者信息

Abrescia Nicola, D'Abbraccio Maurizio, Figoni Mario, Busto Annunziata, Butrico Ettore, De Marco Mario, Viglietti Rosaria

出版信息

J Antimicrob Chemother. 2002 Nov;50(5):763-5. doi: 10.1093/jac/dkf204.

DOI:10.1093/jac/dkf204
PMID:12407142
Abstract
摘要

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1
Fulminant hepatic failure after the start of an efavirenz-based HAART regimen in a treatment-naive female AIDS patient without hepatitis virus co-infection.一名未接受过治疗、无肝炎病毒合并感染的女性艾滋病患者在开始基于依非韦伦的高效抗逆转录病毒治疗方案后发生暴发性肝衰竭。
J Antimicrob Chemother. 2002 Nov;50(5):763-5. doi: 10.1093/jac/dkf204.
2
[Progressive multifocal leukoencephalopathy in patients with AIDS. Hepatotoxicity of HAART therapy in patients with coinfection by HBV or HCV].[艾滋病患者的进行性多灶性白质脑病。合并感染乙肝病毒或丙肝病毒患者接受高效抗逆转录病毒治疗的肝毒性]
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3
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Influence of liver fibrosis on highly active antiretroviral therapy-associated hepatotoxicity in patients with HIV and hepatitis C virus coinfection.肝纤维化对合并感染人类免疫缺陷病毒和丙型肝炎病毒患者高效抗逆转录病毒治疗相关肝毒性的影响。
Clin Infect Dis. 2005 Feb 15;40(4):588-93. doi: 10.1086/427216. Epub 2005 Jan 21.
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Efavirenz-based regimen as treatment of advanced AIDS with cryptococcal meningitis.
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Central nervous system adverse effects with efavirenz: case report and review.
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[Psychiatric diseases and HIV infection. These patients are dually stigmatized].[精神疾病与艾滋病毒感染。这些患者面临双重污名化]
MMW Fortschr Med. 2003 Apr 28;145 Spec No 1:70-2.
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Short communication: oral lesions in HIV/AIDS patients undergoing HAART including efavirenz.简短通讯：接受包括依非韦伦在内的高效抗逆转录病毒治疗的艾滋病毒/艾滋病患者的口腔病变
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Liver injury in HIV-1-infected patients receiving non-nucleosides reverse transcriptase inhibitors-based antiretroviral therapy.HIV-1 感染患者接受非核苷类逆转录酶抑制剂为基础的抗逆转录病毒治疗中的肝损伤。
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["Once daily" drugs simplify therapy. Rp. HAART once daily].["每日一次"的药物简化了治疗方案。高效抗逆转录病毒疗法每日一次] 。 （注：Rp. 此处可能是错误或多余表述，按照字面意思翻译了，但从医学角度看这个 Rp. 在这里不太符合规范用法）
MMW Fortschr Med. 2003 Apr 28;145 Spec No 1:84.

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Hepatotoxicity of Contemporary Antiretroviral Drugs: A Review and Evaluation of Published Clinical Data.当代抗逆转录病毒药物的肝毒性：已发表临床数据的综述与评估。
Cells. 2021 May 20;10(5):1263. doi: 10.3390/cells10051263.
2
Hepatotoxicity and Liver-Related Mortality in Women of Childbearing Potential Living With Human Immunodeficiency Virus and High CD4 Cell Counts Initiating Efavirenz-Containing Regimens.开始含依非韦伦方案的有生育潜力且CD4细胞计数高的感染人类免疫缺陷病毒女性的肝毒性及肝脏相关死亡率
Clin Infect Dis. 2021 Apr 26;72(8):1342-1349. doi: 10.1093/cid/ciaa244.
3
Acute Liver Failure among Patients on Efavirenz-Based Antiretroviral Therapy.
基于依非韦伦的抗逆转录病毒疗法治疗患者中的急性肝衰竭
Case Reports Hepatol. 2018 May 10;2018:1270716. doi: 10.1155/2018/1270716. eCollection 2018.
4
Drug-Induced Liver Injury in HIV Patients.HIV患者的药物性肝损伤
Gastroenterol Hepatol (N Y). 2006 Jun;2(6):430-437.
5
Liver enzyme abnormalities and associated risk factors in HIV patients on efavirenz-based HAART with or without tuberculosis co-infection in Tanzania.坦桑尼亚接受基于依非韦伦的高效抗逆转录病毒治疗的 HIV 患者中，合并或不合并结核分枝杆菌感染时肝酶异常及相关危险因素。
PLoS One. 2012;7(7):e40180. doi: 10.1371/journal.pone.0040180. Epub 2012 Jul 11.
6
Fatal cumulative toxicities of HAART in a stable, AIDS-free, HIV-infected patient.高效抗逆转录病毒治疗（HAART）对一名病情稳定、无艾滋病的HIV感染患者的致命累积毒性。
BMJ Case Rep. 2012 Mar 8;2012:bcr1020114905. doi: 10.1136/bcr.10.2011.4905.
7
Severe cholestatic liver injury days after initiating antiretroviral therapy in a patient with AIDS: drug toxicity or immune reconstitution inflammatory syndrome?一名艾滋病患者在开始抗逆转录病毒治疗数天后出现严重胆汁淤积性肝损伤：是药物毒性还是免疫重建炎症综合征？
Dig Dis Sci. 2005 Oct;50(10):1813-7. doi: 10.1007/s10620-005-2943-8.