van Duijkeren E, Wannet W J B, Houwers D J, van Pelt W
Bacteriology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
J Clin Microbiol. 2002 Nov;40(11):3980-5. doi: 10.1128/JCM.40.11.3980-3985.2002.
We studied serotypes and phage types of Salmonella strains isolated from humans and animals in The Netherlands over the period 1984 to 2001. All human strains (n = 59,168) were clinical isolates. The animal strains (n = 65,567) were from clinical and nonclinical infections. All isolates were serotyped, and Salmonella enterica serovar Typhimurium and serovar Enteritidis strains were further phage typed. The most prevalent serotypes were as follows: in humans, serovars Typhimurium and Enteritidis; in cattle, serovars Typhimurium and Dublin; in pigs, serovar Typhimurium; and in chickens, serovars Enteritidis, Infantis, and Typhimurium. Serovar Enteritidis phage type 4 (pt 4) was the most common phage type in humans and chickens. Serovar Typhimurium pt 510 was the most prevalent serovar Typhimurium phage type in humans and pigs, pt 200 was the most prevalent serovar Typhimurium phage type in cattle, and pt 150 was the most prevalent serovar Typhimurium phage type in chickens. Analysis of the distribution of sero- and phage types during the study period indicated that types shifted over time in humans and animals. Serovar Typhimurium DT 104 emerged in 1991 in humans, cattle, pigs, and chickens and became the most common serovar Typhimurium phage type in 2001. In general, similar sero- and phage types were found in humans and animals, although distinct types were more common in animals. Between the animal species, the sero- and phage type distributions varied considerably.
我们研究了1984年至2001年期间从荷兰人和动物中分离出的沙门氏菌菌株的血清型和噬菌体类型。所有人类菌株（n = 59,168）均为临床分离株。动物菌株（n = 65,567）来自临床和非临床感染。对所有分离株进行血清分型，肠炎沙门氏菌鼠伤寒血清型和肠炎血清型菌株进一步进行噬菌体分型。最常见的血清型如下：在人类中，鼠伤寒血清型和肠炎血清型；在牛中，鼠伤寒血清型和都柏林血清型；在猪中，鼠伤寒血清型；在鸡中，肠炎血清型、婴儿血清型和鼠伤寒血清型。肠炎血清型4型（pt 4）是人类和鸡中最常见的噬菌体类型。鼠伤寒血清型pt 510是人类和猪中最常见的鼠伤寒血清型噬菌体类型，pt 200是牛中最常见的鼠伤寒血清型噬菌体类型，pt 150是鸡中最常见的鼠伤寒血清型噬菌体类型。对研究期间血清型和噬菌体类型分布的分析表明，人类和动物中的类型随时间发生了变化。鼠伤寒血清型DT 104于1991年在人类、牛、猪和鸡中出现，并在2001年成为最常见的鼠伤寒血清型噬菌体类型。一般来说，人类和动物中发现了相似的血清型和噬菌体类型，尽管不同的类型在动物中更常见。在动物物种之间，血清型和噬菌体类型分布差异很大。
