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从丹麦的生产动物和人类中分离出的肠炎沙门氏菌肠炎亚种鼠伤寒血清型的噬菌体类型。

Phage types of Salmonella enterica ssp. enterica serovar typhimurium isolated from production animals and humans in Denmark.

作者信息

Baggesen D L, Wegener H C

机构信息

Danish Veterinary Laboratory, Copenhagen.

出版信息

Acta Vet Scand. 1994;35(4):349-54. doi: 10.1186/BF03548307.

DOI:10.1186/BF03548307
PMID:7676916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8101383/
Abstract

S. Typhimurium is one of the 2 most common salmonella serotypes causing human salmonellosis in Denmark. In order to illustrate the significance of different production animals as a source of infection, 1461 isolates were characterized by phage typing. The isolates originated from human patients and from cattle, pigs and poultry. By phage typing the isolates could be separated in 35 different phage types. Five types (10, 12, 66, 110 and 135) predominated and comprised 78.8% of the isolates. In humans, 57.3% of the isolates were phage type 12. This phage type was also predominant in pig herds and, to a lesser degree, in cattle. Phage types 110, 120, 135 and 193 constituted 86.5% of the poultry isolates while these phage types only made up 12.9% of the human isolates. The investigation showed that pigs are probably a major source of S. Typhimurium infection in humans in Denmark today.

摘要

鼠伤寒沙门氏菌是丹麦导致人类感染沙门氏菌病的两种最常见血清型之一。为了阐明不同生产动物作为感染源的重要性,对1461株分离株进行了噬菌体分型鉴定。这些分离株源自人类患者以及牛、猪和家禽。通过噬菌体分型,这些分离株可分为35种不同的噬菌体类型。其中五种类型(10、12、66、110和135)占主导地位,占分离株的78.8%。在人类中,57.3%的分离株为噬菌体12型。这种噬菌体类型在猪群中也占主导地位,在牛群中占比相对较小。噬菌体110、120、135和193型占家禽分离株的86.5%,而这些噬菌体类型仅占人类分离株的12.9%。调查表明,如今在丹麦,猪可能是人类感染鼠伤寒沙门氏菌的主要来源。