Frangakis Constantine E, Varadhan Ravi
Department of Biostatistics, John Hopkins University, Baltimore, MD 21205, USA.
Epidemiology. 2002 Nov;13(6):734-7. doi: 10.1097/00001648-200211000-00022.
In evaluating the relative risk of seasonality, the null value is a boundary value. In this case, tests for the null hypothesis exist, but standard methods for confidence intervals are not appropriate. We provide a method for constructing confidence intervals under the circular normal model. The proposed confidence intervals are valid for all values of the underlying seasonal risk if the model is correct and for the null boundary value of the seasonal risk, regardless of model assumptions and sample size. We apply our method to seasonal suicide data from a recent report.
在评估季节性的相对风险时,零值是一个边界值。在这种情况下,存在对原假设的检验,但用于构建置信区间的标准方法并不适用。我们提供了一种在圆正态模型下构建置信区间的方法。如果模型正确,所提出的置信区间对于潜在季节性风险的所有值都是有效的,并且对于季节性风险的零边界值也是有效的,而与模型假设和样本量无关。我们将我们的方法应用于最近一份报告中的季节性自杀数据。