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苏格兰二手婴儿床垫与婴儿猝死综合征:病例对照研究

Used infant mattresses and sudden infant death syndrome in Scotland: case-control study.

作者信息

Tappin David, Brooke Hazel, Ecob Russell, Gibson Angus

机构信息

Scottish Cot Death Trust, Department of Child Health, Royal Hospital for Sick Children, Glasgow G3 8SJ.

出版信息

BMJ. 2002 Nov 2;325(7371):1007. doi: 10.1136/bmj.325.7371.1007.

Abstract

OBJECTIVE

To examine the proposition that a used infant mattress is associated with an increased risk of sudden infant death syndrome.

DESIGN

Case-control study.

SETTING

Scotland (population 5.1 million, with about 53 000 births a year).

PARTICIPANTS

131 infants who died of sudden infant death syndrome between 1 January 1996 and 31 May 2000 and 278 age, season, and obstetric unit matched control infants.

MAIN OUTCOME MEASURES

Routine use of an infant mattress previously used by another child and place of last sleep.

RESULTS

Routine use of an infant mattress previously used by another child was significantly associated with an increased risk of sudden infant death syndrome (multivariate odds ratio 3.07, 95% confidence interval 1.51 to 6.22). Use of a used infant mattress for last sleep was also associated with increased risk (6.10, 2.31 to 16.12). The association was significantly stronger if the mattress was from another home (4.78, 2.08 to 11.0) than if it was from the same home (1.64, 0.64 to 4.2).

CONCLUSION

A valid significant association exists between use of a used infant mattress and an increased risk of sudden infant death syndrome, particularly if the mattress is from another home. Insufficient evidence is available to judge whether this relation is cause and effect.

摘要

目的

检验二手婴儿床垫与婴儿猝死综合征风险增加相关这一命题。

设计

病例对照研究。

背景

苏格兰(人口510万,每年约有5.3万例出生)。

参与者

1996年1月1日至2000年5月31日期间死于婴儿猝死综合征的131名婴儿,以及278名年龄、季节和产科病房匹配的对照婴儿。

主要观察指标

常规使用曾被另一个孩子用过的婴儿床垫以及最后睡眠地点。

结果

常规使用曾被另一个孩子用过的婴儿床垫与婴儿猝死综合征风险增加显著相关(多变量优势比3.07,95%置信区间1.51至6.22)。最后睡眠时使用二手婴儿床垫也与风险增加相关(6.10,2.31至16.12)。如果床垫来自另一个家庭,这种关联显著更强(4.78,2.08至11.0),而如果来自同一个家庭则较弱(1.64,0.64至4.2)。

结论

使用二手婴儿床垫与婴儿猝死综合征风险增加之间存在有效的显著关联,尤其是当床垫来自另一个家庭时。尚无足够证据判断这种关系是否为因果关系。

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