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中东欧儿童的呼吸道症状、支气管炎和哮喘。

Respiratory symptoms, bronchitis and asthma in children of Central and Eastern Europe.

作者信息

Leonardi G S, Houthuijs D, Nikiforov B, Volf J, Rudnai P, Zejda J, Gurzau E, Fabianova E, Fletcher T, Brunekreef B

机构信息

Environmental Epidemiology Unit, London School of Hygiene and Tropical Medicine, UK.

出版信息

Eur Respir J. 2002 Oct;20(4):890-8. doi: 10.1183/09031936.02.00260802.

Abstract

The multicentre Central European Study of Air Pollution and Respiratory Health (CESAR) aimed to measure the respiratory health of schoolchildren using a standardised questionnaire in six countries of Central and Eastern Europe (CEE), allowing comparisons within this region and with other European countries. A cross-sectional study was conducted in 25 urban areas of Bulgaria, Czech Republic, Hungary, Poland, Romania, and Slovakia in 1996. Parents of 21,743 schoolchildren of age 7-11 yrs completed a questionnaire based on items from the World Health Organization and International Study of Asthma and Allergies in Childhood questions on cough and wheeze symptoms, as well as on diagnoses by doctors. Life-time prevalence of bronchitis was 55.9%, asthma 3.9%, and asthmatic, spastic or obstructive bronchitis 12.3%. In CEE countries the prevalence of bronchitis is higher and prevalence of asthma appears lower than in Western Europe. However, if asthma is defined as a diagnosis of either asthma or asthmatic, spastic or obstructive bronchitis, then its prevalence is comparable to Western Europe, or higher. In this region, within-country variation for most respiratory parameters is less than between-country variation. Between-country comparisons in doctors' diagnoses appear dependent on the choice of definition of asthma. Europe-wide comparisons in prevalence of respiratory symptoms and diagnosis are reported in this study. Some of the East-West difference in asthma prevalence may be attributable to differences in diagnostic practice.

摘要

多中心的中欧空气污染与呼吸健康研究(CESAR)旨在通过标准化问卷,对中东欧(CEE)六个国家的学童呼吸健康状况进行测量,以便在该地区内部以及与其他欧洲国家之间进行比较。1996年,在保加利亚、捷克共和国、匈牙利、波兰、罗马尼亚和斯洛伐克的25个城市地区开展了一项横断面研究。21743名7至11岁学童的家长完成了一份基于世界卫生组织及儿童哮喘与过敏国际研究的问卷,内容涉及咳嗽和喘息症状以及医生的诊断。支气管炎的终生患病率为55.9%,哮喘为3.9%,哮喘性、痉挛性或阻塞性支气管炎为12.3%。在中东欧国家,支气管炎的患病率较高,哮喘的患病率似乎低于西欧。然而,如果将哮喘定义为哮喘或哮喘性、痉挛性或阻塞性支气管炎的诊断,那么其患病率与西欧相当,或更高。在该地区,大多数呼吸参数的国家内部差异小于国家之间的差异。医生诊断的国家间比较似乎取决于哮喘定义的选择。本研究报告了全欧洲范围内呼吸症状患病率和诊断情况的比较。哮喘患病率的一些东西方差异可能归因于诊断实践的差异。

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