Zenebe W, Pechanova O
Bratisl Lek Listy. 2002;103(4-5):159-65.
Phenolic phytochemicals are widely distributed in the plant kingdom. Regarding the protective effects on organisms, the polyphenol group is the most important. In different experiments, it has been shown that selected polyphenols, mainly flavonoids, possess protective effects on the cardiovascular system, as well as anticancer, antiviral and antiallergic properties. In coronary heart disease, the protective effects include mainly antithrombic, antioxidant, anti-ischaemic and vasorelaxant properties of flavonoids. It has been hypothesised that the phenomenon of a low incidence of coronary heart disease in French people may be partially related to the pharmacological properties of polyphenolic compounds included in red wine. Many epidemiological studies have shown that regular flavonoid intake is associated with reduced risk of cardiovascular diseases. This review article discusses the chemical structure of polyphenols and their beneficial properties in the cardiovascular system. (Fig. 1, Ref 74.).
酚类植物化学物质广泛分布于植物界。就对生物体的保护作用而言，多酚类是最重要的。在不同实验中已表明，所选多酚，主要是黄酮类化合物，对心血管系统具有保护作用，还具有抗癌、抗病毒和抗过敏特性。在冠心病中，其保护作用主要包括黄酮类化合物的抗血栓形成、抗氧化、抗缺血和血管舒张特性。据推测，法国人冠心病发病率较低的现象可能部分与红酒中所含多酚类化合物的药理特性有关。许多流行病学研究表明，经常摄入黄酮类化合物与心血管疾病风险降低有关。这篇综述文章讨论了多酚的化学结构及其在心血管系统中的有益特性。（图1，参考文献74。）
