Lozoya Xavier, Reyes-Morales Hortensia, Chávez-Soto Marco A, Martínez-García María del Carmen, Soto-González Yolanda, Doubova Svetlana V
Laboratory of Medicinal Plants at Research Unit of Neurological Diseases, Mexican Institute of Social Security (IMSS), Mexico City, Mexico.
J Ethnopharmacol. 2002 Nov;83(1-2):19-24. doi: 10.1016/s0378-8741(02)00185-x.
Ancestral medicinal use of guava (Psidium guajava L. Fam. Myrtaceae) is today supported by numerous biomedical studies concerning the properties of leaf extracts. However, insufficient clinical studies are reported on the use of this plant resource in the treatment of gastrointestinal ailments. The present work reports a randomized, double-blinded, clinical study performed to evaluate the safety and efficacy of a phytodrug (QG-5) developed from guava leaves, standardized in its content of quercetin and orally administered to a group of adult patients with acute diarrheic disease. Capsules containing 500 mg of the product were administered to 50 patients every 8 h during 3 days. Results obtained showed that the used guava product decreased the duration of abdominal pain in these patients.
番石榴（番石榴属桃金娘科）的传统药用价值如今得到了众多关于叶提取物特性的生物医学研究的支持。然而，关于这种植物资源用于治疗胃肠道疾病的临床研究报道不足。本研究报告了一项随机、双盲临床研究，旨在评估一种由番石榴叶制成的植物药（QG - 5）的安全性和有效性，该植物药的槲皮素含量已标准化，并口服给予一组患有急性腹泻疾病的成年患者。在3天内，每8小时给50名患者服用含有500毫克该产品的胶囊。获得的结果表明，所使用的番石榴产品缩短了这些患者腹痛的持续时间。
