Porhanov Vladimir A, Poliakov Igor S, Selvaschuk Andrew P, Grechishkin Anatoly I, Sitnik Sergei D, Nikolaev Igor F, Efimtsev Jury P, Marchenko Leonid G
Krasnodar Regional Thoracic Surgery Center, Sity Hospital 2, 6\2 Krasnykh Partizan Street, Krasnodar 350012, Russia.
Eur J Cardiothorac Surg. 2002 Nov;22(5):685-94. doi: 10.1016/s1010-7940(02)00523-7.
Carinal resection is the most complicated procedure in tracheobronchial surgery. The main aspects of the technique are still debated at the present time. We present our experience of 231 carinal resections with analysis of operative techniques, complications and long-term survival.
Since 1979 we have performed 231 carinal resections. Indications for surgery included lung cancer in 151 cases (65.4%), non-bronchogenic carcinoma in 45 (19.4%), main bronchus fistula with short stump in 25 (10.8%), stenosis of tuberculous and nonspecific etiology in nine (4%), and trauma in one case (0.4%). We have performed 156 right-sided resections (67.5%) and 75 left-sided (32.5%). In 162 cases carinal pneumonectomy was undertaken, carinal resection following pneumonectomy was performed in 28 cases, isolated resection of bronchial bifurcation was performed in 25 cases, and in 15 cases we combined lobectomy and resection of bifurcation. The length of resection extended from one to nine tracheal rings. The operative approach was lateral thoracotomy in 102 cases (44.2%), and sternotomy in 129 (55.8%).
Thirty-seven patients died postoperatively (16%). Complications were observed in 82 patients (35.4%), dominated by anastomotic problems which occurred in 58 cases (25.1%). The most frequent causes of death were respiratory distress syndrome and anastomotic dehiscence (P < 0.05). Mortality and the incidence of complications were significantly correlated to length of resection, laryngeal nerves injury, and mode of intraoperative ventilation.
The feasibility of carinal resection is limited by the patient's functional status and extension of tumor growth. Thorough selection of patients may improve immediate and long-term results.
隆突切除是气管支气管外科中最复杂的手术。目前该技术的主要方面仍存在争议。我们介绍231例隆突切除的经验,并分析手术技术、并发症及长期生存率。
自1979年以来,我们共进行了231例隆突切除。手术适应证包括肺癌151例(65.4%)、非支气管源性癌45例(19.4%)、主支气管瘘伴短残端25例(10.8%)、结核及非特异性病因导致的狭窄9例(4%)、创伤1例(0.4%)。我们进行了156例右侧切除(67.5%)和75例左侧切除(32.5%)。162例行隆突肺切除术,28例行肺切除术后隆突切除,25例行支气管分叉孤立切除,15例联合肺叶切除及分叉切除。切除长度从1个气管环至9个气管环。手术入路102例(44.2%)采用侧开胸,129例(55.8%)采用胸骨正中切开。
37例患者术后死亡(16%)。82例患者(35.4%)出现并发症,以吻合口问题为主,共58例(25.1%)。最常见的死亡原因是呼吸窘迫综合征和吻合口裂开(P<0.05)。死亡率和并发症发生率与切除长度、喉返神经损伤及术中通气方式显著相关。
隆突切除的可行性受患者功能状态及肿瘤生长范围的限制。严格筛选患者可改善近期及远期效果。