Nicholson Matthew, Beal Matthew, Shofer Frances, Brown Dorothy Cimino
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104, USA.
Vet Surg. 2002 Nov-Dec;31(6):577-81. doi: 10.1053/jvet.2002.34661.
To evaluate risk factors for development of postoperative wound infections in clean-contaminated wounds.
Retrospective clinical study.
Two hundred thirty-nine dogs and cats that had clean-contaminated surgical procedures.
Records of animals that had a clean-contaminated surgical procedure and were prospectively monitored for development of postoperative wound infection were reviewed. Prospective data included signalment, nutritional status, body weight, duration of surgery, surgical procedures, wound classification, surgical site clip time before surgery, hypotension during surgery, the presence of an active distant infection, endocrinopathy, administration of an immunosuppressive agent, administration of antibiotics, and the type of antibiotic used. Additional retrieved data included total anesthesia time, temperature variables, blood loss, and suture material used.
Intact males (P =.008) and animals with concurrent endocrinopathy (P =.008) were at a higher risk of development of postoperative wound infection. Total surgery time (P =.02) and total anesthesia time (P =.04) were longer in animals that developed postoperative wound infection. No other factors were statistically significant.
Intact males and animals with a concurrent endocrinopathy were at higher risk of postoperative wound infection after clean-contaminated surgical procedures.
Time under anesthesia and duration of surgery should be minimized to reduce the risk of wound infection in clean-contaminated surgical procedures.
评估清洁-污染伤口术后伤口感染发生的危险因素。
回顾性临床研究。
239只接受清洁-污染外科手术的犬猫。
回顾接受清洁-污染外科手术且对术后伤口感染发生情况进行前瞻性监测的动物记录。前瞻性数据包括特征、营养状况、体重、手术时长、手术操作、伤口分类、术前手术部位备皮时间、术中低血压、存在活动性远处感染、内分泌病、免疫抑制剂的使用、抗生素的使用以及所用抗生素的类型。另外获取的数据包括总麻醉时间、体温变量、失血量和所用缝合材料。
未绝育雄性动物（P = 0.008）和并发内分泌病的动物（P = 0.008）术后伤口感染发生风险更高。发生术后伤口感染的动物手术总时长（P = 0.02）和总麻醉时间（P = 0.04）更长。无其他因素具有统计学意义。
未绝育雄性动物和并发内分泌病的动物在接受清洁-污染外科手术后发生术后伤口感染的风险更高。
在清洁-污染外科手术中，应尽量缩短麻醉时间和手术时长，以降低伤口感染风险。
