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从猫和狗的骨科手术后手术部位感染中分离需氧菌。

Isolation of aerobic bacteria from surgical site infections following orthopaedic operations in cats and dogs.

作者信息

Gulaydin Ali, Gulaydin Ozgul, Akgul Mustafa Baris

机构信息

Department of Surgery, Faculty of Veterinary Medicine, Siirt University, Siirt, Turkiye.

Department of Microbiology, Faculty of Veterinary Medicine, Siirt University, Siirt, Turkiye.

出版信息

Vet Med (Praha). 2024 Jul 29;69(7):243-253. doi: 10.17221/26/2024-VETMED. eCollection 2024 Jul.

DOI:10.17221/26/2024-VETMED
PMID:39221121
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11359976/
Abstract

Surgical site infections (SSIs) cause significant complications in the postoperative period in veterinary surgeries. Determining the aetiology of infections is crucial for increasing treatment success rates. This study aims to assess treatment processes by identifying the bacterial agents responsible for infections occurring in cats and dogs after orthopaedic operations and to determine the antimicrobial resistance profiles of these agents. Strains isolated from SSIs were retrospectively analysed in patients brought to the Surgical Clinic of Siirt University Animal Health Application and Research Hospital between 2021 and 2023. The isolates were identified using MALDI-TOF MS. The disc diffusion method was applied to determine the antimicrobial susceptibility of the isolates. A high isolation rate was detected in methicillin-resistant and extended-spectrum beta-lactamase (ESBL) producing . According to the antimicrobial susceptibility results, cephalosporin treatment was continued in only one of the cases in which prophylactic treatment with cephalosporin group antibiotics was applied. Consequently, this study revealed that preoperative prophylactic antibiotic administration may not be sufficient in preventing surgical site infections. Diagnosis of aetiological agents and evaluation of antimicrobial susceptibility are essential in preventing surgical site infections and determining effective treatment options.

摘要

手术部位感染(SSIs)在兽医外科手术后的恢复期会引发严重并发症。确定感染的病因对于提高治疗成功率至关重要。本研究旨在通过识别导致猫和狗骨科手术后感染的细菌病原体来评估治疗过程,并确定这些病原体的抗菌药物耐药性特征。对2021年至2023年间送至锡尔特大学动物健康应用与研究医院外科诊所的患者中从手术部位感染分离出的菌株进行回顾性分析。使用基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)对分离株进行鉴定。采用纸片扩散法测定分离株的抗菌药物敏感性。在耐甲氧西林和产超广谱β-内酰胺酶(ESBL)的菌株中检测到较高的分离率。根据抗菌药物敏感性结果,在应用头孢菌素类抗生素进行预防性治疗的病例中,只有一例继续使用头孢菌素治疗。因此,本研究表明术前预防性使用抗生素可能不足以预防手术部位感染。确定病原体并评估抗菌药物敏感性对于预防手术部位感染和确定有效的治疗方案至关重要。