Ben-Aroya Z, Hallak M, Segal D, Friger M, Katz M, Mazor M
Department of Obstetrics and Gynecology, Edith Wolfson Medical Center, Holon, Israel.
J Matern Fetal Neonatal Med. 2002 Jul;12(1):42-5. doi: 10.1080/jmf.12.1.42.45.
To compare the success and complication rates of prostaglandin E2 tablets (PGE2) and a Foley catheter for the ripening of the uterine cervix in post-Cesarean section parturients.
The study population in this retrospective cohort study consisted of parturients in their second pregnancy who had undergone Cesarean section in their previous delivery and who underwent ripening of the uterine cervix by using PGE2 (n = 55) or Foley catheter (n = 161) in the current pregnancy. The control group consisted of 1432 post-Cesarean section parturients without induction of labor. We compared the rates of placental abruption, non-reassuring fetal heart rate patterns, intrapartum fetal deaths (IPFD), uterine rupture, Apgar scores, labor dystocia, severe birth canal lacerations, vacuum deliveries and repeated Cesarean section rates in the three groups by using ANOVA, chi2 analysis and Fisher's exact test when appropriate.
A significant increase in the rates of labor dystocia during the first stage (30.4% vs. 11.6%, p < 0.01) and repeated Cesarean deliveries (49.1% vs. 35.2%, p < 0.01) were observed in women in whom the Foley catheter was used as compared to controls, respectively. No such changes were demonstrated in the PGE2 group as compared to the controls. No significant differences were found between the PGE2 group and Foley catheter group as compared to the controls in rates of placental abruption, IPFD, uterine rupture, fetal distress, birth canal lacerations, vacuum deliveries and Apgar scores.
PGE2 was found to be superior to the Foley catheter for ripening of the uterine cervix in a post-Cesarean parturient, as demonstrated by a lower repeated Cesarean delivery rate.
比较前列腺素E2片(PGE2)和Foley尿管用于剖宫产术后产妇宫颈成熟的成功率及并发症发生率。
本回顾性队列研究的研究对象为第二次妊娠的产妇,她们既往有剖宫产史,本次妊娠采用PGE2(n = 55)或Foley尿管(n = 161)进行宫颈成熟。对照组由1432例未引产的剖宫产术后产妇组成。我们在适当的时候使用方差分析、卡方检验和Fisher精确检验比较了三组的胎盘早剥、胎儿心率异常、产时胎儿死亡(IPFD)、子宫破裂、阿氏评分、产程难产、严重产道裂伤、真空吸引分娩和再次剖宫产率。
与对照组相比,使用Foley尿管的女性第一产程产程难产率(30.4%对11.6%,p < 0.01)和再次剖宫产率(49.1%对35.2%,p < 0.01)均显著增加。与对照组相比,PGE2组未出现此类变化。与对照组相比,PGE2组和Foley尿管组在胎盘早剥、IPFD、子宫破裂、胎儿窘迫、产道裂伤、真空吸引分娩和阿氏评分方面无显著差异。
在剖宫产术后产妇宫颈成熟方面,PGE2优于Foley尿管,表现为再次剖宫产率较低。