Robinson Dudley, Cardozo Linda
King's College Hospital, 8 Devonshire Place, London W1G GHP, UK.
Curr Urol Rep. 2002 Dec;3(6):452-7. doi: 10.1007/s11934-002-0096-2.
The prevalence of urinary incontinence is known to increase with age, affecting 15% to 35% of community-dwelling women over 60 years of age. Other studies report a prevalence of 49% in women over 65 years of age. Epidemiologic studies have implicated estrogen deficiency in the etiology of lower urinary tract symptoms, although the role of estrogen replacement therapy remains controversial. This review presents recent evidence regarding the role of estrogen in lower urinary tract dysfunction, with a particular emphasis on the management of postmenopausal women with symptoms suggestive of overactive bladder.
已知尿失禁的患病率会随着年龄增长而增加，影响着60岁以上社区居住女性的15%至35%。其他研究报告称65岁以上女性的患病率为49%。流行病学研究表明雌激素缺乏与下尿路症状的病因有关，尽管雌激素替代疗法的作用仍存在争议。本综述介绍了关于雌激素在下尿路功能障碍中作用的最新证据，特别强调对有膀胱过度活动症症状的绝经后女性的管理。
