Schulte T
Arch Toxicol. 1975 Oct 20;34(2):153-8. doi: 10.1007/BF00353316.
A case of a rare lethal intoxication with yew leaves (taxus baccata) is reported. The clinical signs were dizziness (onset 1 hr after yew leaves were ingested), nausea, diffuse abdominal pain, unconsciousness, weak breathing, tachycardia, brief ventricular flutter afterwards a slow pulse, and finally death by respiratory arrest and diastolic cardiac standstill. Particular attention was given to the ECG. It showed an atypical bundle branch block with a maximal QRS-duration of 0.24 sec. A striking resemblence to the ECG in the case of hyperkalemia is seen in that P-waves were absent. Therefore, the possibility is noted that an acute hyperkalemia could be partly responsible for the cardiotoxic effect of the leaf.
报告了一例罕见的致命性红豆杉叶中毒病例。临床症状为头晕(摄入红豆杉叶后1小时发作)、恶心、弥漫性腹痛、昏迷、呼吸微弱、心动过速、随后出现短暂室性扑动及脉搏缓慢,最终因呼吸骤停和舒张期心脏停搏死亡。特别关注了心电图。心电图显示非典型束支传导阻滞,最大QRS时限为0.24秒。与高钾血症病例的心电图有显著相似之处,即P波消失。因此,注意到急性高钾血症可能部分导致了树叶的心脏毒性作用。