Loux Tara J, Haricharan Ramanath N, Clements Ronald H, Kolotkin Ronette L, Bledsoe Samuel E, Haynes Beverly, Leath Teresa, Harmon Carroll M
Division of Pediatric Surgery, University of Alabama at Birmingham Hospital, Birmingham, AL 35233, USA.
J Pediatr Surg. 2008 Jul;43(7):1275-9. doi: 10.1016/j.jpedsurg.2008.02.078.
Recent data reaffirm decreased health-related quality of life (HRQL) in obese adults and children. Health-related quality of life is markedly improved after bariatric surgery in adults. Little HRQL data are available in adolescents undergoing bariatric surgery.
Sixteen patients (14-20 years old) underwent gastric bypass. Thirteen patients completed a general HRQL measure (Short Form 36 [SF-36]) before surgery. Of these, 9 completed the SF-36 again at various follow-up times, as well as a measure of weight-related quality of life (Impact of Weight on Quality of Life-Lite). Three patients completed postsurgical forms only. Data were analyzed using t test and analysis of variance. Results are reported as mean +/- SD.
Mean age and body mass index at operation were 18.5 +/- 1.7 years and 54 +/- 7.6 kg/m(2). Postoperatively, patients lost an average of 66% +/- 29% excess weight over a mean follow-up of 17 +/- 12 (range, 1-39) months. Mean preoperative SF-36 physical component score was 34.7 +/- 10 and mental component score was 40.6 +/- 13.5 (adult population mean = 50.0 +/- 10 for each). At last follow-up, mean physical component score had increased to 55.5 +/- 5, and mental component score, to 55.2 +/- 8.6 (P < .0001). Adolescent Impact of Weight on Quality of Life-Lite scores after surgery did not differ from means for normal weight adults (93% +/- 7% vs 96% +/- 7%, P = .15).
Health-related quality of life in adolescents and young adults undergoing bariatric surgery improves dramatically in early follow-up. Long-term data are needed to definitively study this surgical therapy for obesity in adolescents.
近期数据再次证实肥胖成人和儿童的健康相关生活质量（HRQL）下降。成人接受减肥手术后，健康相关生活质量显著改善。关于接受减肥手术的青少年的HRQL数据很少。
16例患者（14 - 20岁）接受了胃旁路手术。13例患者在手术前完成了一项通用的HRQL测量（简短健康调查问卷36项简表[SF - 36]）。其中9例在不同的随访时间再次完成了SF - 36，以及一项与体重相关的生活质量测量（体重对生活质量的影响-简化版）。3例患者仅完成了术后表格。使用t检验和方差分析对数据进行分析。结果以均值±标准差报告。
手术时的平均年龄和体重指数分别为18.5±1.7岁和54±7.6kg/m²。术后患者在平均17±12（范围1 - 39）个月的随访中平均减轻了66%±29%的超重体重。术前SF - 36身体成分得分平均为34.7±10，心理成分得分平均为40.6±13.5（成人总体均值每项均为50.0±10）。在最后一次随访时，身体成分得分平均增加到55.5±5，心理成分得分增加到55.2±8.6（P <.0001）。青少年术后体重对生活质量的影响-简化版得分与正常体重成年人的均值无差异（93%±7%对96%±7%，P = 0.15）。
接受减肥手术的青少年和青年在早期随访中健康相关生活质量显著改善。需要长期数据来明确研究这种针对青少年肥胖的手术治疗方法。
