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不同饮食条件下的酒精吸收与消除(作者译)

[Alcohol absorption and elimination in different alimentary conditions (author's transl)].

作者信息

Weinel H, Kruse-Jarres J D

出版信息

Arzneimittelforschung. 1975 Oct;25(10):1655-9.

PMID:1243053
Abstract

The continuous enzymatic in vivo estimation of blood alcohol was used for plotting curves of blood alcohol concentrations in 24 double-experiments from 4 to 6 h duration. Absorption and elimination of alcohol were observed under the influence of the food eaten before. Two hours after a light meal test persons drank whisky and blood alcohol curves were recorded determining increase, maximum and elimination. The curves varied especially in the phases of absorption. In a second test compared with the curves after a light meal the retardation of absorption was examined after drinking the juice of "Sangritta picante" spice in addition. Delayed alcohol absorption could be verified. After taking a fat meal the retardation of absorption was found even greater. Recorded after fasting for more than 12 h the curves showed a slower increase in blood alcohol concentration and a higher maximum in comparison with the curves after a light meal.

摘要

采用连续酶法在体内测定血液酒精含量,用于绘制24次双盲实验中持续4至6小时的血液酒精浓度曲线。在进食前食物的影响下观察酒精的吸收和消除情况。在清淡餐后两小时,测试对象饮用威士忌,并记录血液酒精曲线,以确定酒精的增加、最大值和消除情况。这些曲线在吸收阶段尤其有所不同。在第二项测试中,与清淡餐后的曲线相比,在饮用“辛辣桑格里塔”香料汁后,研究了吸收的延迟情况。可以证实酒精吸收延迟。进食高脂餐后,发现吸收延迟更为明显。在禁食超过12小时后记录的曲线显示,与清淡餐后的曲线相比,血液酒精浓度的上升较慢,最大值较高。

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