一例由苯妥英引起的超敏反应综合征。

A case of hypersensitivity syndrome due to phenytoin.

作者信息

Nagai Yayoi, Hattori Tomoyasu, Ishikawa Osamu

机构信息

Department of Dermatology, Tone Central Hospital, Numata, Gunma, Japan.

出版信息

J Dermatol. 2002 Oct;29(10):670-3. doi: 10.1111/j.1346-8138.2002.tb00201.x.

DOI:10.1111/j.1346-8138.2002.tb00201.x

PMID:12433002

Abstract

We report a 30-year-old female with hypersensitivity syndrome (HS) due to phenytoin. Her disease course was typical with elevation of the antibody titer for human herpes virus 6. Three courses of methylpredonisolone pulse therapy were required to control the disease activity. Since the pathogenic mechanism and treatments for HS have not been established, further clinical analyses are warranted.

摘要

我们报告一例30岁因苯妥英钠导致超敏反应综合征（HS）的女性患者。其病程典型，人疱疹病毒6型抗体滴度升高。需要3个疗程的甲泼尼龙冲击疗法来控制疾病活动。由于HS的发病机制和治疗方法尚未明确，有必要进行进一步的临床分析。