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Spatial heterogeneity in the heart: recent insights and open questions.

作者信息

Decking Ulrich K M

机构信息

Institut für Herz- und Kreislaufphysiologie, Heinrich-Heine-Universität Düsseldorf, Germany.

出版信息

News Physiol Sci. 2002 Dec;17:246-50. doi: 10.1152/nips.01393.2002.

DOI:10.1152/nips.01393.2002
PMID:12433979
Abstract

Within the left ventricular myocardium and despite its rather homogeneous structure, local myocardial perfusion varies substantially. Areas of low and high local flow differ with regard to substrate uptake, energy turnover, and demand. This spatial heterogeneity is related to distinct differences in local protein expression, forming the basis of a novel homeostatic mechanism.

摘要

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