Lauer Thomas, Kleinbongard Petra, Kelm Malte
Klinik für Kardiologie, Pneumologie, und Angiologie, Heinrich-Heine-Universität Düsseldorf, Germany.
News Physiol Sci. 2002 Dec;17:251-5. doi: 10.1152/nips.01405.2002.
Disturbances of nitric oxide (NO) bioavailability may play a key role in vascular dysfunction and in the development of atherosclerotic lesions. Thus assessment of a reduced NO bioavailability in human circulation is of particular interest. Here we summarize potential biomarkers of NO availability in human blood and critically discuss their respective significance and application fields.
一氧化氮（NO）生物利用度的紊乱可能在血管功能障碍和动脉粥样硬化病变的发展中起关键作用。因此，评估人体循环中NO生物利用度降低具有特别重要的意义。在这里，我们总结了人体血液中NO可用性的潜在生物标志物，并批判性地讨论了它们各自的意义和应用领域。
