Bellamy N, Campbell J, Haraoui B, Gerecz-Simon E, Buchbinder R, Hobby K, MacDermid J C
The Faculty of Health Sciences, The University of Queensland, Herston, Australia.
Osteoarthritis Cartilage. 2002 Nov;10(11):863-9. doi: 10.1053/joca.2002.0838.
To assess the reliability, validity and responsiveness of the Australian/Canadian (AUSCAN) Osteoarthritis Hand Index in both Likert (LK) and Visual Analogue (VA)-scaled formats.
Two separate studies were conducted; the first addressing reliability and validity issues and the second addressing index responsiveness. In a group of 50 patients with osteoarthritis (OA) of the hand, test-retest reliability was assessed at a 1-week interval and internal consistency from single administrations of the Index. Construct validity was evaluated against several other outcome measures including the Functional Index for Hand Osteoarthritis (FIHOA), separate patient and physician global assessments, Doyle Index, grip strength, pinch grip, and Health Assessment Questionnaire. A 6-week washout retreatment design was used in a group of 44 OA hand patients to assess index responsiveness and comparative responsiveness against the FIHOA.
Reliability and construct validity coefficients confirm the reliability and construct validity of both the AUSCAN LK3.0 and AUSCAN VA3.0 Indices. The washout retreatment study establishes index responsiveness and suggests that the AUSCAN LK3.0 and AUSCAN VA3.0 Indices may be more responsive than the FIHOA.
The patient self-completed AUSCAN LK3.0 and AUSCAN VA3.0 Indices are reliable, valid and responsive and can be recommended as primary outcome measures for future hand OA clinical trials.
评估澳大利亚/加拿大（AUSCAN）骨关节炎手部指数在李克特（LK）量表和视觉模拟（VA）量表两种形式下的信度、效度和反应度。
进行了两项独立研究；第一项研究解决信度和效度问题，第二项研究解决指数反应度问题。在一组50例手部骨关节炎（OA）患者中，以1周为间隔评估重测信度，并通过单次使用该指数评估内部一致性。通过与其他几种结局指标进行比较来评估结构效度，这些指标包括手部骨关节炎功能指数（FIHOA）、患者和医生分别进行的整体评估、多伊尔指数、握力、捏力以及健康评估问卷。在一组44例手部OA患者中采用6周洗脱期再治疗设计，以评估该指数的反应度以及与FIHOA相比的相对反应度。
信度和结构效度系数证实了AUSCAN LK3.0和AUSCAN VA3.0指数的信度和结构效度。洗脱期再治疗研究确定了指数反应度，并表明AUSCAN LK3.0和AUSCAN VA3.0指数可能比FIHOA更具反应度。
患者自行完成的AUSCAN LK3.0和AUSCAN VA3.0指数具有信度、效度和反应度，可推荐作为未来手部OA临床试验的主要结局指标。
