McQuillan Thomas J, Vora Molly M, Kenney Deborah E, Crisco Joseph J, Weiss Arnold-Peter C, Ebert Kerry A, Snelgrove Kathleen E, Sarnowski Alexandra, Ladd Amy L
1 Stanford University, CA, USA.
2 Brown University, Providence, RI, USA.
Hand (N Y). 2018 Nov;13(6):652-658. doi: 10.1177/1558944717729217. Epub 2017 Sep 21.
The Australian/Canadian Osteoarthritis Hand Index (AUSCAN) and Patient-Rated Wrist-Hand Evaluation (PRWHE) are 2 patient-related outcome measures to assess pain and disability in patients with osteoarthritis (OA). The purpose of this study was to evaluate the AUSCAN and PRWHE in a large-scale, longitudinal cohort of patients with early thumb carpometacarpal (CMC) OA.
We obtained baseline data on 135 individuals (92 with early CMC OA participants and 43 asymptomatic controls) and at follow-up (year 1.5) on 83 individuals. We assessed the internal consistency using Cronbach alpha, and construct and criterion validity using other pain scales and objective measures of strength, respectively. We also examined the correlation between the AUSCAN and PRWHE and correlation coefficients at baseline and follow-up, as well as the correlation between changes in these instruments over the follow-up period.
Internal consistency was high for both AUSCAN and PRWHE totals and subscales (Cronbach α > 0.70). Both instruments demonstrated construct validity compared with the Verbal Rating Scale ( r = 0.52-0.60, P < .01), an assessment of pain, and moderate criterion validity compared with key pinch and grip strength ( r = -.24 to -.33, P < .05). These instruments were highly correlated with each other at baseline and follow-up time points ( r = 0.76-.94, P < .01), and changes in a patient's total scores over time were also correlated ( r = 0.83, P < .01).
The AUSCAN and PRWHE are both valid assessments for pain and/or disability in patients with early thumb CMC OA.
澳大利亚/加拿大骨关节炎手部指数(AUSCAN)和患者自评腕手评估(PRWHE)是用于评估骨关节炎(OA)患者疼痛和功能障碍的两项患者相关结局指标。本研究的目的是在一个大规模的早期拇指腕掌关节(CMC)OA患者纵向队列中评估AUSCAN和PRWHE。
我们获取了135名个体(92名早期CMC OA参与者和43名无症状对照者)的基线数据,并在随访时(1.5年)获取了83名个体的数据。我们分别使用Cronbach α评估内部一致性,并使用其他疼痛量表和力量客观测量指标评估结构效度和效标效度。我们还检查了AUSCAN和PRWHE之间的相关性以及基线和随访时的相关系数,以及这些工具在随访期间变化之间的相关性。
AUSCAN和PRWHE总分及各子量表的内部一致性均较高(Cronbach α>0.70)。与用于评估疼痛的视觉模拟评分量表相比,这两种工具均显示出结构效度(r = 0.52 - 0.60,P <.01),与关键捏力和握力相比,显示出中等效标效度(r = -0.24至-0.33,P <.05)。这些工具在基线和随访时间点彼此高度相关(r = 0.76 - 0.94,P <.01),并且患者总分随时间的变化也具有相关性(r = 0.83,P <.01)。
AUSCAN和PRWHE都是评估早期拇指CMC OA患者疼痛和/或功能障碍的有效工具。