Arnold N I
JAMA. 1975 Jan 6;231(1):56-7. doi: 10.1001/jama.231.1.56.
Results of 261 paracervical blocks done with a dose of 12 ml of 1% chloroprocaine hydrochloride solution containing 1:200,000 epinephrine were recorded. The blocks were followed by abnormal heart rate patterns for 3 to 15 minutes in six of 104 (5.8%) of the fetuses. Excellent pain relief was obtained with 142 of 172 blocks or 83%. One fetus died owing to multiple congenital anomalies. Paracervical blocks performed as described are completely safe for the mother and do not affect Apgar scores. Potential fetal risks are acceptable when considered in light of the ease of administration and the amount of pain relief obtained.
记录了261例宫颈旁阻滞的结果，所用药物为12毫升含1:200,000肾上腺素的1%盐酸氯普鲁卡因溶液。在104例胎儿中的6例（5.8%），阻滞操作后出现了3至15分钟的异常心率模式。172例阻滞中有142例（83%）获得了良好的疼痛缓解效果。有1例胎儿因多种先天性畸形死亡。按所述方法进行的宫颈旁阻滞对母亲完全安全，且不影响阿氏评分。鉴于给药的简便性和所获得的疼痛缓解程度，潜在的胎儿风险是可以接受的。
