Hwang Juen-Haur, Chu Chih-Kai, Liu Tien-Chen
Department of Otolaryngology, Poh-Ai Hospital, Lotung, Taiwan.
J Laryngol Otol. 2002 Sep;116(9):686-9. doi: 10.1258/002221502760237957.
A bacteriological study on 161 consecutive out-patients presenting with otorrhoea was performed prospectively at a local teaching hospital in Taiwan between August 2000 and June 2001. A total of 177 isolates were recovered. Staphylococcus aureus was found in 77 (43.5 per cent) isolates, and non-Staphylococcus aureus in 100 (56.5 per cent) isolates. Pseudomas sp was found to be the most common pathogen (28.8 per cent) in the non-Staphylococcus aureus group. Staphylococcus aureus had become more common than Pseudomonas aeruginosa in acute otitis externa, granular myringitis, and chronic otitis media in Taiwan. Methicillin-resistant Staphylococcus aureus (MRSA) was also an increasing problem in all three disease entities. The prevalence of community-acquired MRSA infections in discharging ears was found to be 13.7 per cent (22/161). MRSAs were highly susceptible to vancomycin, teicoplanin, fusidic acid, and minocycline. More studies should be done to determine the susceptibility of MRSA to ofloxacin in the future.
2000年8月至2001年6月期间,在台湾一家当地教学医院对161例连续性门诊耳漏患者进行了前瞻性细菌学研究。共分离出177株菌株。在77株(43.5%)菌株中发现了金黄色葡萄球菌,在100株(56.5%)菌株中发现了非金黄色葡萄球菌。假单胞菌属被发现是非金黄色葡萄球菌组中最常见的病原体(28.8%)。在台湾,金黄色葡萄球菌在急性外耳道炎、颗粒性鼓膜炎和慢性中耳炎中比铜绿假单胞菌更为常见。耐甲氧西林金黄色葡萄球菌(MRSA)在这三种疾病中也是一个日益严重的问题。在耳漏患者中,社区获得性MRSA感染的患病率为13.7%(22/161)。MRSA对万古霉素、替考拉宁、夫西地酸和米诺环素高度敏感。未来应进行更多研究以确定MRSA对氧氟沙星的敏感性。