Manipulating the environment of cancer cells in bone: a novel therapeutic approach.
作者信息
Martin T John
机构信息
St. Vincent's Institute of Medical Research, and Department of Medicine, University of Melbourne, Melbourne, Australia.
出版信息
J Clin Invest. 2002 Nov;110(10):1399-401. doi: 10.1172/JCI17124.
Abstract
摘要
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本文引用的文献
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Guanosine nucleotides inhibit different syndromes of PTHrP excess caused by human cancers in vivo.鸟苷酸在体内可抑制人类癌症引起的不同类型的甲状旁腺激素相关蛋白过量综合征。
J Clin Invest. 2002 Nov;110(10):1559-72. doi: 10.1172/JCI11936.
2
Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor.甲状旁腺激素相关肽是一种天然存在的、蛋白激酶A依赖性血管生成抑制剂。
Nat Med. 2002 Sep;8(9):995-1003. doi: 10.1038/nm753. Epub 2002 Aug 19.
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Metastasis to bone: causes, consequences and therapeutic opportunities.骨转移：病因、后果及治疗机遇
Nat Rev Cancer. 2002 Aug;2(8):584-93. doi: 10.1038/nrc867.
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Involvement of parathyroid hormone-related protein in experimental cachexia induced by a human lung cancer-derived cell line established from a bone metastasis specimen.甲状旁腺激素相关蛋白在由源自骨转移标本建立的人肺癌细胞系诱导的实验性恶病质中的作用。
Int J Cancer. 2001 Oct 1;94(1):24-7. doi: 10.1002/ijc.1425.
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Transforming growth factor beta regulates parathyroid hormone-related protein expression in MDA-MB-231 breast cancer cells through a novel Smad/Ets synergism.转化生长因子β通过一种新的Smad/Ets协同作用调节MDA-MB-231乳腺癌细胞中甲状旁腺激素相关蛋白的表达。
J Biol Chem. 2001 Dec 7;276(49):46661-70. doi: 10.1074/jbc.M105816200.
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Parathyroid hormone-related protein production by breast cancers, improved survival, and reduced bone metastases.
J Natl Cancer Inst. 2001 Feb 7;93(3):234-7. doi: 10.1093/jnci/93.3.234.
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Science. 2000 Sep 1;289(5484):1508-14. doi: 10.1126/science.289.5484.1508.
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A novel orthotopic model of breast cancer metastasis to bone.一种新型的乳腺癌骨转移原位模型。
Clin Exp Metastasis. 1999 Mar;17(2):163-70. doi: 10.1023/a:1006689719505.
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Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families.肿瘤坏死因子受体和配体家族新成员对破骨细胞分化和功能的调节
Endocr Rev. 1999 Jun;20(3):345-57. doi: 10.1210/edrv.20.3.0367.
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