Tolu W, Fadda F, Carbini L, Padalino A
S TA NU. 1975 Sep-Dec;5(5-6):315-6.
We studied the intestinal glucose absorption in a colony of rats at different ages. The experiment was carried out on animals of the following ages: 3, 5, 10 and 20 months. All rats were fasted 48 hr prior to the administration of 2 ml. 50% glucose solution by an oesophageal sound. After one hour the animals were killed, the intestine was washed with a determinated quantity of distilled water and homogenized, to find out any trace of glucose in mucose cells. Glucose absorption was calculated as the difference between the quantity introduced and that left in the intestine. The results of this experiment show that glucose absorption expressed as mg/100 gm. body weight/hr decrease significantly during the first 10 months, with no marked changes there after. Absorption rapidly increase during the first 16 month, if expressed as mg/hr. This is probably due to a remarkable weight increase without a proportional increase of intestinal length.
我们研究了不同年龄大鼠群体的肠道葡萄糖吸收情况。实验选用了以下年龄的动物：3个月、5个月、10个月和20个月。所有大鼠在通过食管探子给予2毫升50%葡萄糖溶液前禁食48小时。一小时后处死动物，用一定量蒸馏水冲洗肠道并匀浆，以检测黏膜细胞中是否有葡萄糖痕迹。葡萄糖吸收量通过摄入的葡萄糖量与肠道中剩余葡萄糖量的差值来计算。该实验结果表明，以毫克/100克体重/小时表示的葡萄糖吸收量在前10个月显著下降，之后无明显变化。若以毫克/小时表示，在最初16个月内吸收量迅速增加。这可能是由于体重显著增加而肠道长度未相应增加所致。
