Nomura Jason T, Sato Renee L, Ahern Reina M, Snow Joanne L, Kuwaye Todd T, Yamamoto Loren G
Emergency Department, Kapiolani Medical Center For Women And Children, University of Hawaii John A. Burns School of Medicine, Honolulu, HI, USA.
Am J Emerg Med. 2002 Nov;20(7):624-6. doi: 10.1053/ajem.2002.35710.
The objective of the study was to compare cutaneous treatments (heat, papain and vinegar) for acute jellyfish (Carybdea alata) stings. Healthy adult volunteer subjects received a single-tentacle jellyfish sting on each forearm. One forearm was treated with hot-water immersion (40-41 degrees C). This was compared with the other forearm, which was randomized to a comparison treatment of papain meat tenderizer or vinegar. Pain was measured at 0, 2, 4, 6, 8, 10, 15, and 20 minutes using a 10-cm visual analog scale (VAS). For 25 subject runs, the average VAS scores at t = 0 were 3.6 cm (hot water) and 3.7 cm (comparison treatment). At t = 4 minutes (2 minutes after treatment had started), the differences between hot-water and comparison group VAS scores were 2.1 cm versus 3.2 cm, respectively. The mean difference between hot-water and comparison treatments was 1.1 cm (95% confidence interval, 0.6 to 1.6). At t = 20 minutes (the end of the study period), the differences between hot-water and comparison group VAS scores were 0.2 cm versus 1.8 cm, respectively. The mean difference between hot-water and comparison treatments was 1.6 cm (95% confidence interval, 0.9 to 2.3). This study suggests that the most efficacious initial treatment for C alata jellyfish envenomation is hot-water immersion to the afflicted site.
该研究的目的是比较针对急性僧帽水母（Carybdea alata）蜇伤的皮肤治疗方法（热敷、木瓜蛋白酶和醋）。健康的成年志愿者受试者每只前臂接受单触手僧帽水母蜇伤。一只前臂采用热水浸泡治疗（40 - 41摄氏度）。将其与另一只前臂进行比较，后者随机接受木瓜蛋白酶嫩肉剂或醋的对照治疗。使用10厘米视觉模拟量表（VAS）在0、2、4、6、8、10、15和20分钟时测量疼痛程度。在25次受试者试验中，t = 0时的平均VAS评分，热水组为3.6厘米，对照治疗组为3.7厘米。在t = 4分钟（治疗开始后2分钟）时，热水组与对照组的VAS评分差异分别为2.1厘米和3.2厘米。热水治疗与对照治疗的平均差异为1.1厘米（95%置信区间，0.6至1.6）。在t = 20分钟（研究期结束时），热水组与对照组的VAS评分差异分别为0.2厘米和1.8厘米。热水治疗与对照治疗的平均差异为1.6厘米（95%置信区间，0.9至2.3）。该研究表明，对于僧帽水母蜇伤最有效的初始治疗方法是对患处进行热水浸泡。
