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黄貂鱼蜇伤:119例临床症状及治疗的回顾性研究

Stingray envenomation: a retrospective review of clinical presentation and treatment in 119 cases.

作者信息

Clark Richard F, Girard Robyn Heister, Rao Daniel, Ly Binh T, Davis Daniel P

机构信息

Division of Medical Toxicology, Department of Emergency Medicine, University of California, San Diego Medical Center, San Diego, California, USA.

出版信息

J Emerg Med. 2007 Jul;33(1):33-7. doi: 10.1016/j.jemermed.2007.03.043. Epub 2007 May 30.

Abstract

Stingray stings are common along coastal regions of this country and the world. The tail of the stingray contains a barbed stinger attached to a venom gland and contained within an integumentary sheath. During a sting, the stinger and sheath can become embedded in the soft tissue of the victim, and venom is injected into the wound. Stingray venom most often causes severe pain on contact, although the exact mechanism of toxicity is not certain. Hot water immersion of the stung extremity has been reported to be effective in relieving pain associated with the envenomation, but large studies of this therapy have not been performed. We retrospectively reviewed stingray stings presenting to our Emergency Department (ED) over an 8-year period. Cases were divided into acute (group 1, within 24 h of the sting) and subacute (group 2, 24 h or more after the sting) presentations. Charts were abstracted for information concerning the victim's history, physical examination, treatment, diagnostic imaging, and outcome, including the effectiveness of hot water immersion as analgesia, and use of antimicrobials. A total of 119 cases were identified and abstracted, 100 in group 1 and 19 in group 2. Of the group 1 patients initially treated with hot water immersion alone, 88% had complete relief of pain within 30 min without administration of any other analgesic. In the patients who initially received a dose of analgesic along with hot water immersion, none required a second dose of analgesics and all had complete pain relief before discharge. There were no adverse effects (such as thermal burns) with this therapy. Analysis of infectious complications in group 1 patients demonstrated a significant number of patients returning to the ED with wound infections when prophylactic antibiotics were not administered at initial presentation. Our findings suggest that hot water immersion was effective in decreasing or eliminating the pain associated with stingray envenomation in our series. Due to the high potential for bacterial contamination in these puncture wounds, standard antibiotic prophylaxis may be prudent. Although stingray barbs can be radio-opaque, radiography in our series failed to detect barbs or other foreign bodies in stung extremities, although no barbs or other stinger material were found on inspection of wounds.

摘要

魟鱼蜇伤在该国及全球沿海地区都很常见。魟鱼的尾巴上有一根带倒刺的毒刺,与毒腺相连,并包裹在一个皮肤鞘内。蜇伤时,毒刺和鞘会嵌入受害者的软组织中,毒液会注入伤口。魟鱼毒液接触时通常会引起剧痛,但其确切的毒性机制尚不确定。据报道,用热水浸泡被蜇伤的肢体可有效缓解与中毒相关的疼痛,但尚未对该疗法进行大规模研究。我们回顾性分析了8年间在我们急诊科就诊的魟鱼蜇伤病例。病例分为急性(第1组,蜇伤后24小时内)和亚急性(第2组,蜇伤后24小时或更长时间)表现。提取病历以获取有关受害者病史、体格检查、治疗、诊断成像和结果的信息,包括热水浸泡作为镇痛方法的有效性以及抗菌药物的使用情况。共识别并提取了119例病例,第1组100例,第2组19例。在最初仅用热水浸泡治疗的第1组患者中,88%在30分钟内疼痛完全缓解,未使用任何其他镇痛药。在最初接受一剂镇痛药并同时进行热水浸泡的患者中,没有人需要第二剂镇痛药,并且所有患者在出院前疼痛完全缓解。该疗法没有不良反应(如热烧伤)。对第1组患者感染并发症的分析表明,在初次就诊时未使用预防性抗生素的情况下,大量患者因伤口感染返回急诊科。我们的研究结果表明,在我们的系列病例中,热水浸泡可有效减轻或消除与魟鱼蜇伤相关的疼痛。由于这些刺伤伤口存在高度的细菌污染可能性,进行标准的抗生素预防可能是明智的。尽管魟鱼的倒刺可能是不透射线的,但在我们的系列病例中,X线检查未能在被蜇伤的肢体中检测到倒刺或其他异物,尽管在检查伤口时未发现倒刺或其他毒刺物质。

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