Dubova E A, Podgornova M N, Shchegolev A I
Arkh Patol. 2010 Sep-Oct;72(5):30-2.
The authors present the data available in the literature and the results of their studies of intraoperative specimens from 24 patients with mucinous cystic tumors of the pancreas. The latter are a special group of neoplasms that are unrelated to the gland's ducts and consist of the mucin-producing epithelium with underlying ovarian-like stroma. Mucinous cystadenocarcinoma are detectable in older women (mean age 54.8 years), they are large and multicompartmental in nature. Microscopic study has indicated that all types of mucinous cystic tumors are characterized by ovarian-like stroma, the cells of which show a positive reaction to progesterone receptor antibodies. More significant ovarian-like stroma is typical of mucinous cystadenoma. The high (more than 30%) proliferative activity of epithelial lining cells is suggestive of the malignant nature of the process.
