Amozorrutia-Alegría Víctor, Bravo-Ortiz Juan Carlos, Vázquez-Viveros Josefina, Campos-Campos Laura, Mejía-Aranguré Manuel, Juárez-Ocaña Servando, Martínez-García María del Carmen, Fajardo-Gutiérrez Arturo
Clinical Epidemiology Medical Research Unit, Regional General Hospital no 24, IMSS, Mexico.
Paediatr Perinat Epidemiol. 2002 Oct;16(4):370-4. doi: 10.1046/j.1365-3016.2002.t01-1-00442.x.
The object of this study is to present descriptive epidemiological characteristics of retinoblastoma (Rb) in children aged 0-14 years, seen at the Mexican Social Security Institute hospitals in Mexico City (MC) from 1990 to 1994. This is a retrospective, observational hospital survey. Clinical records of 52 Rb cases were reviewed; 39 were patients who did not reside in MC (non-residents), and 13 were MC residents. The study period was 1990-94. The male/female ratio (M/F) was 1.6. Average annual incidence (AAI) was estimated by age and sex (rates per 1000000). Annual average percentage change (AAPC) in incidence rates was estimated in children from 0 to 14 years. The AAI for MC residents was 3.2; the highest rate being for those <1 year olds (rate of 20.8); AAPC was 6.9% [95% CI -27.5, 57.4]; the highest incidence was for the south-eastern region of MC residents (rate of 5.9); 13 cases (25%) were diagnosed at stage III or IV, and 11 cases (21.2%) were bilateral. Incidence of Rb is similar to that in developed countries and shows no increasing trend. Patients from communities outside MC are more frequently diagnosed at stages III and IV.
本研究的目的是呈现1990年至1994年在墨西哥城墨西哥社会保障局医院就诊的0至14岁儿童视网膜母细胞瘤（Rb）的描述性流行病学特征。这是一项回顾性观察性医院调查。对52例Rb病例的临床记录进行了审查；39例为不住在墨西哥城的患者（非居民），13例为墨西哥城居民。研究期间为1990 - 1994年。男/女比例（M/F）为1.6。按年龄和性别估计年均发病率（每1000000人发病率）。估计0至14岁儿童发病率的年均百分比变化（AAPC）。墨西哥城居民的年均发病率为3.2；1岁以下儿童发病率最高（为20.8）；AAPC为6.9%[95%置信区间 -27.5, 57.4]；墨西哥城居民中东南部地区发病率最高（为5.9）；13例（25%）在III期或IV期确诊，11例（21.2%）为双侧。Rb发病率与发达国家相似，且无上升趋势。来自墨西哥城以外社区的患者在III期和IV期确诊的频率更高。
