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缓释洗必泰芯片对牙周综合征临床及微生物学参数的影响。

Effect of a controlled-release chlorhexidine chip on clinical and microbiological parameters of periodontal syndrome.

作者信息

Grisi Daniela C, Salvador Sérgio L, Figueiredo Luciene C, Souza Sérgio L S, Novaes Arthur B, Grisi Márcio F M

机构信息

Department of Buco-Maxillofacial Surgery and Traumatology and Periodontology, School of Dentistry of Ribeirão Preto, Brazil.

出版信息

J Clin Periodontol. 2002 Oct;29(10):875-81. doi: 10.1034/j.1600-051x.2002.291001.x.

Abstract

AIM

The aim of this study was to evaluate the effectiveness of a controlled-released chlorhexidine chip (CHX) as adjunctive therapy to scaling and root planing (SRP) in the treatment of chronic periodontitis.

MATERIAL AND METHODS

Twenty patients with at least four sites with probing depth >or= 5 mm and bleeding on probing were selected. This randomized single-blind study was carried out in parallel design. The control group received SRP alone, while the test group received SRP plus CHX chip. The clinical parameters, Plaque Index (PlI), Papillary Bleeding Score (PBS), Bleeding on Probing (BOP), Gingival Recession (GR), Probing Depth (PD) and Relative Attachment Level (RAL), and the microbiological parameter BANA test were recorded at baseline and after 3, 6 and 9 months.

RESULTS

Both groups presented significant improvements in all parameters analyzed over the study period. There were no statistically significant differences between the two groups for any parameter analyzed after 9 months, except for BOP, which was significantly reduced in the control group. The mean reductions on PD and RAL were 2.4 mm and 1.0 mm for the control group and 2.2 mm and 0.6 mm for the test group, respectively.

CONCLUSION

The CHX chip did not provide any clinical or microbiological benefit beyond that achieved with conventional scaling and root planning, after a 9-month period.

摘要

目的

本研究旨在评估缓释洗必泰芯片(CHX)作为辅助疗法联合龈下刮治和根面平整术(SRP)治疗慢性牙周炎的有效性。

材料与方法

选取20例至少有4个探诊深度≥5mm且探诊出血位点的患者。本随机单盲研究采用平行设计。对照组仅接受SRP治疗,而试验组接受SRP联合CHX芯片治疗。在基线以及3、6和9个月后记录临床参数,包括菌斑指数(PlI)、龈乳头出血评分(PBS)、探诊出血(BOP)、牙龈退缩(GR)、探诊深度(PD)和相对附着水平(RAL),以及微生物学参数BANA试验。

结果

在研究期间,两组在所有分析参数上均有显著改善。9个月后,除BOP外,两组在任何分析参数上均无统计学显著差异,BOP在对照组中显著降低。对照组PD和RAL的平均减少量分别为2.4mm和1.0mm,试验组分别为2.2mm和0.6mm。

结论

9个月后,CHX芯片并未提供超出传统龈下刮治和根面平整术的临床或微生物学益处。

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