Femi-Pearse D, Afonja A O, Elegbeleye O O, Odusote K A
Br Med J. 1976 Jan 10;1(6001):74-5. doi: 10.1136/bmj.1.6001.74.
Oxygen consumption (VO2) was determined in 10 patients with moderate tetanus. The mean (+/- SE) VO2 of 425-2-2 +/- 50-3 ml/min on admission fell significantly to 249-9 +/- 13-1 ml/min standard temperature and pressure dry (STPD) after parenteral diazepam. There was also a significant fall in minute ventilation after administration of diazepam. The results suggest that the simple practical determination of VO2 will be of immense value in assessing the efficacy of muscle relaxants, assessing the severity of tetanus, and determining the calorie needs of patients.
对10例中度破伤风患者测定了耗氧量（VO2）。入院时平均（±标准误）VO2为425.2±50.3 ml/min，经静脉注射地西泮后，在标准温度、标准气压及干燥条件下（STPD）显著降至249.9±13.1 ml/min。注射地西泮后分钟通气量也显著下降。结果表明，简单实用的VO2测定对于评估肌肉松弛剂的疗效、评估破伤风的严重程度以及确定患者的热量需求具有巨大价值。
